Displaying 743 (all) recruiting clinical trials.
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RESPONSE: A Placebo-controlled Randomized Phase 3 Study to Evaluate the Efficacy and Safety of Seladelpar in Patients With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)
The purpose of this study, which involves research, is to determine if an investigational drug, seladelpar,is safe and effective in treating patients with PBC ...Phase
Interventional
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Osteolysis following nonmetallic suture anchor use in hand and wrist surgery
The purpose of this study is to study the effects of nonmetallic suture anchors on the bones of the hand and wrist. Suture anchors are ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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Elucidating Neural Mechanisms and Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder
The purpose of this research study is to understand to how Mindfulness-Based Stress Reduction (MBSR)compared to a Stress Education (SE) class works for patients ...Phase N/A Interventional
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An Interventional Multi-Center investigation of Single Level Transforaminal Lumber Interbody Fusion (TLIF) Stabilized with Pedicle Screws
This research study is being conducted to collect data on the safety and effectiveness of a transforaminal lumbar interbody fusion (TLIF) procedure. This is the ...Phase N/A Interventional
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A Phase 2 Trial of the Combination of Polatuzumab Vedotin Venetoclax and Rituximab and Hyaluronidase Human for Relapsed and Refractory Mantle Cell Lymphoma
The purpose of the study is to evaluate the activity of a novel triplet combination of rituximab and hyaluronidase human, polatuzumab vedotin, and venetoclax for ...Phase
Interventional
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A Phase 3 Multi-center Randomized Double-blinded Study of MK-7684 with Pembrolizumab as a Co-formulation (MK-7684A) Versus Pembrolizumab Monotherapy as a First Line Treatment for Participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung Cancer
The purpose of the study is to determine and compare MK-7684A to pembrolizumab alone for participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung ...Phase
Interventional
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A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
The primary objectives of this study are to determine the recommended phase 2 dose(s) (RP2Ds) of JNJ-75276617, as well as the safety and tolerability ...Phase
Interventional
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Hunter Outcome Survey: A Global Multi-Center Long-Term Observational Registry of Patients with Hunter Syndrome
The purpose of the Hunter Outcome Survey (HOS) is to monitor the long-term safety and effectiveness of enzyme replacement therapy (ERT) with Elaprase in patients ...Phase
Non-Interventional
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Utility of ImmuKnow an Immune Cell Function Assay in a Cardiac Sarcoid Population
The purpose of this study is to assess whether the results of an immune cell function blood test, ImmuKnow can be used to predict responses ...Phase N/A Non-Interventional
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A Prospective Multicenter Study to Evaluate the Perioperative Outcomes of Robotic-assisted Revisional Bariatric Surgery
The purpose of this study is to collect and evaluate data and short-term clinical outcomes from the robotic-assisted minimally invasive approach of bariatric revisional surgery ...Phase N/A Non-Interventional
