Displaying 114 (all) recruiting clinical trials.
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Proactive infliximab optimization using a pharmacokinetic dashboard versus standard of care in patients with Crohn s disease: The OPTIMIZE Trial
This is a randomized, controlled, multicenter, open-label study. All eligible subjects will be randomly assigned in a 1:1 ratio to receive either IFX monotherapy ...Phase N/A
Interventional
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AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs.Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
The aim of this study for low and standard risk germ cell tumor (GCT) patients is to minimize toxicity by reducing therapy while maintaining current ...Phase
Interventional
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ACNS2021: A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in ...Phase
Interventional
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Phase 3 multicenter randomized double-blind group sequential placebo-controlled study to assess efficacy and safety of rimegepant for the treatment of migraine (with or without aura) in children and adolescents = 6 to
The main purpose of this study is to learn how well the study drug works and how safe the study drug is in children and ...Phase
Interventional
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Movement Disorder Genomic Study
With the present study we aim to perform integrated genomic analysis and study on subject-specific cellular models in order to identify genetic causes of rare ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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Genetic Screening Outcomes in Movement Disorders
Understanding the correlation between genetic mutations and causative pathogenic mechanisms and phenotypes in Movement Disorders may significantly contribute to implementing therapeutic approaches for these conditions ...Phase N/A Non-Interventional
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Psoriatic Response and Onset: Genes Radiology Environment Skin and Synovium)
This is a longitudinal, observational cohort study to aimed to understand the clinical and biologic underpinnings of psoriasis and psoriatic arthritis development and severity. To ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Wolff-Parkinson-White Syndrome in Children
This is a prospective study with the aim to create a database of pediatric patients with Wolff-Parkinson-White syndrome. The overarching goal is to provide information ...Phase N/A Non-Interventional
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ACNS1931: A Phase 3 Study of Selumetinib (NSC# 748727 IND# 77782) or Selumetinib in Combination with Vinblastine for non-NF1 non-TSC Patients with Recurrent or Progressive Low-Grade Gliomas (LGGs) Lacking BRAFV600E or IDH1 Mutations
This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib ...Phase
Interventional
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Registry for SETD2 Neurodevelopmental Disorder
This study involves the collection of data from individuals who have SETD2-neurodevelopmental disorders. By collecting clinical information and administering surveys to affected individuals or their ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
