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Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)
The purpose of this study is to compare the effectiveness and safety of meniscal repair in 2 groups of patients: meniscal repair with biological augmentation ... -
A Phase III Randomized Double-Blind Placebo-Controlled Multicenter Study to Evaluate the Efficacy Safety Pharmacokinetics and Pharmacodynamics of Satralizumab as Monotherapy or in Addition to Baseline Therapy in Patients with Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
The purpose of this study is to compare the effects, good or bad, of satralizumab with placebo alone or in combination with current treatment (baseline ... -
Optimized MRI of patients with hip arthroplasty
In patients with hip replacement, the metal of the artificial hip darkens the magnetic resonance imaging (MRI) images which is called shadowing. The purpose of ... -
A Phase 1b/2 Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants with Advanced or Metastatic Colorectal Cancer.
You can participate in this study if you are diagnosed with histologically or cytologically confirmed unresectable or metastatic adenocarcinoma of the colon or rectum. The ... -
A Phase 1/1b Open-label Multicenter Study to Investigate the Safety Tolerability Pharmacokinetics and Antitumor Activity of KIN-2787 in Participants with BRAF and/or NRAS Mutation-positive Solid Tumors.
You can participate in this study if you are diagnosed with stage 3 or stage 4 skin melanoma. The purpose of this study is to ... -
Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE)
You can participate in this study if you are newly diagnosed with brain cancer (glioblastoma). The purpose of this study is to evaluate a peptide ...
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Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis
The purpose of this research study is to see whether ticagrelor and aspirin or rivaroxaban and aspirin compared to clopidogrel and aspirin will have the ... -
A Randomized Controlled Trial of Alternating Irrigation of Vancomycin HCl and Tobramycin Sulfate in Patients Undergoing Two-Stage Exchange Arthroplasty for Periprosthetic Joint Infection of Hip or Knee.
The purpose of this research is to study how safe and effective the VT-X7 Treatment System is when used to irrigate the wound after your ... -
Recovering Sense of Smell in COVID-19 Long Haulers
The purpose of this research study is to evaluate the efficacy of a treatment for COVID-19 related changes in your sense of smell. This study ... -
Health Evaluation Allostatic Load Multiple Sclerosis (HEAL-MS)
The role of childhood adversity has yet to be examined in pediatric-onset MS, despite data demonstrating that childhood adversity has been linked to earlier age ...