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DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs
Aspirin is commonly used to prevent heart attacks and strokes in clinical care. Commonly a “baby” aspirin (81mg) is prescribed for this purpose. However, higher ... -
A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02D
The purpose of the study is to determine the efficacy of investigational agents with or without pembrolizumab for the treatment of PD-1 naïve or PD-1 ... -
STK-001-DS-501 - An Open-Label Extension Study for Patients with Dravet Syndrome who Previously Participated in Studies of STK 001
The purpose of this research study is to look at a possible new therapy for Dravet syndrome, called STK-001. Dravet syndrome is a severe form ... -
Reverse End to Side Transfer for Severe Cubital Tunnel Syndrome
The purpose of this research study is to look for differences in outcomes between two different surgical treatments for cubital tunnel syndrome. -
Mesoscopic Biomarkers of Neurodegeneration and Inflammation with Diffusion MRI
The purpose of this study is to track both neurodegeneration and inflammation in multiple sclerosis (MS) disease progression by taking pictures using Magnetic Resonance Imaging ... -
A Prospective Registry for the Study of Outcomes and Predictors in Pouchitis and Pouch-Related Disorders
The purpose of this study is to collect information of patients with pouch-related conditions. The information gathered during the study will help us know more ... -
Studies of Patients with Implanted Intracranial Electrodes
This research is being done to study different methods for mapping the areas of the human brain responsible for speech, language, hearing, vision, sensation, movement ... -
The DIAbetes TELEmedicine MEDiterranean Diet Study (DIATELEMED)
The purpose of this research study is to compare 3 different dietary management approaches for achieving blood sugar control for people with early-stage type 2 ... -
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Adjuvant Chemotherapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1 BRCA2 or PALB2 Mutation
This phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic cancer that ... -
A Single-Center Observational Study of the Impact of Tremor Affecting the Voice on Deglutition
The purpose of this study is to examine tremor that affect people's voices. This will be done by collecting information associated with the evaluation ...