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Feasibility and Safety of Geniculate Artery Embolization for Treatment of Mild to Moderate Knee Osteoarthritis
The purpose of this study is to evaluate the safety and feasibility of genicular artery embolization using EmbozeneTM microspheres for mild-to-moderate knee osteoarthritis (OA) detected ...Phase N/A
Interventional
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A randomized Phase I/II trial of fulvestrant and abemaciclib in combination with copanlisib (FAC) versus fulvestrant and abemaciclib alone (FA) for endocrine-resistant hormone receptor positive HER2 negative metastatic breast cancer (FAC vs FA)
The purpose of the study is to determine the effects (good and bad) of adding copanlisib to the usual therapy of fulvestrant and abemaciclib in ...Phase
Interventional
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Phase II pilot study of FOLFOXIRI plus panitumumab in metastatic RAS wild-type left-sided colorectal cancer
The purpose of this study is to evaluate the effectiveness (percent of patients with measurable response) of FOLFOXIRI and panitumumab for treatment of metastatic left ...Phase
Interventional
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Prediction of Recurrent Anterior Shoulder Instability Using the On/Off Track Method and 3D MRI: A Clinical Outcomes and Cost-Effectiveness Study
The purpose of this study is to see whether a new imaging-based measurement technique, On/Off Track method, will be able to predict the failure ...Phase N/A
Non-Interventional
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A Phase 3 Randomized Double-blind Matching Placebo-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) versus CRT Alone in Participants with MIBC (KEYNOTE-992)
The purpose of the study is to determine the safety and efficacy of Pembrolizumab (MK-3475) and Chemoradiotherapy (CRT) for people who have muscle-invasive bladder cancer ...Phase
Interventional
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Comparison of office-based KTP and CO2 laser outcomes in patients with vocal cord lesions.
The purpose of this study is to test the outcomes of a CO2 laser device called AcuPulse Duo on vocal lesions and compare them to ...Phase N/A Interventional
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A Post-Market Clinical Evaluation of the Treatment of Femur Fractures with the Femoral Nail Greater Trochanter (GT) of the T2 Alpha Femur Antegrade GT/PF Nailing System
The purpose of this study is to show the safety and performance of the T2 Alpha Femur Antegrade Greater Trochanter (GT) Nail. Participants will be ...Phase
Interventional
Accepts Healthy Volunteer
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The use of cannabidiol (CBD) in pain reduction and opioid use after shoulder arthroscopy: A Double-Blind Randomized Control Study
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) following shoulder arthroscopic surgery can lessen post- surgical pain and ...Phase
Interventional
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Knotless Suture in Revision Total Joint Arthroplasty: A Prospective Randomized Controlled Trial
The purpose of this research study is to compare the differences between two surgical closure techniques by looking at closure time and all post-operative wound ...Phase N/A Interventional
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A Phase 1 Study to Evaluate the Safety and Tolerability of AB680 Combination Therapy in Participants with Gastrointestinal Malignancies
The purpose of this study is to understand whether potential new drugs, AB680 and AB122, can be safely given to patients with pancreatic cancer in ...Phase
Interventional
