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Anti-viral therapy in Alzheimer's disease
This study is being conducted to evaluate if the generic anti-viral medication, valacyclovir, is helpful in treating Alzheimer's disease in patients who have tested positive ...Phase
Interventional
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Transcranial Direct Current Stimulation (tDCS) for the Management of Multiple Sclerosis Related Fatigue
The purpose of this study is to determine if tDCS (short for transcranial direct current stimulation) can be used to manage the MS symptoms of ...Phase
Interventional
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Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients with Functional Iron Deficiency
The purpose of this study is to better understand how body levels of iron affect the ability to exercise in patients with heart failure. Heart ...Phase
Interventional
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A single arm open-label multicenter phase II study of 177Lu-DOTATATE radionuclide in adults with progressive or high-risk meningioma
The purpose of this research study is to test whether Lutathera® (177Lu-DOTATATE) is effective (how well something works) at stopping the growth of meningiomas. This ...Phase
Interventional
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Effects of N-Acetyl-L-Leucine on GM2 Gangliosidosis (Tay-Sachs and Sandhoff Disease): A multinational multicenter open-label rater-blinded Phase II study.
The purpose of this study is to investigate if the study drug N-Acetyl-L-Leucine, called IB1001, can help improve the symptoms of GM2 Gangliosidosis after 6-weeks ...Phase
Interventional
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A Phase 2 multicenter randomized double-blind placebo-controlled study to assess the efficacy safety and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of neurobehavioral disinhibition including aggression agitation and irritability in patients with traumatic brain injury (TBI)
Symptoms associated with TBI such as physical and verbal aggression, agitation and irritability are problematic, can be difficult to manage, can be disruptive, and can ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination with Ipilimumab and Nivolumab in Patients with Unresectable Stage III or Stage IV Melanoma
The main purpose of this study is to test the safety, tolerability, and effectiveness of the study drug tocilizumab when given with the drugs ipilimumab ...Phase
Interventional
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Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes- RADAR
The purpose of this study is to evaluate heart rhythms in patients who are being treated with hemodialysis. This research will see how these heart ...Phase
Interventional
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Fenflurmaine in CKDL5 Deficiency Disorder (CDD)
The purpose of this study is to study the effectivenss of treating CDKL5 Deficiency Disorder with Fenfluramine. This treatment uses an investigational drug named fenfluramine ...Phase
Interventional
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Radiation Dermatitis: A phase 1 randomized double blinded placebo controlled study of the safety and efficacy of a caffeine-based antifibrosis cream in patients with breast cancer undergoing radiation therapy (ReDCoAT Study)
The purpose of the study is to evaluate whether a caffeine-based cream can reduce the rates of complications in patients with tissue expander based reconstruction ...Phase
Interventional
