-
Phenotypic and genotypic study of Keratoconus
Keratoconus is a disease in which the cornea is abnormally steep and thin. It affects approximately 1 in 2000 individuals and usually begins in the ...Phase N/A
Non-Interventional
-
Simultaneous Multinuclear Magnetic Resonance Fingerprinting for Data Fusion of Quantitative Structural and Metabolic Imaging
This proposal seeks to perform an observational study, for evaluating a new non-invasive imaging technique that will provide multi-parametric metabolic 3D maps of the living ...Phase N/A Non-Interventional
-
A pragmatic trial to evaluate the intermediate-term effects of early aggressive versus escalation therapy in people with multiple sclerosis
The TREAT-MS trial (TRaditional versus Early Aggressive Therapy for MS) is a pragmatic, randomized controlled trial that has two primary aims: 1) to evaluate, jointly ...Phase N/A
Interventional
-
In Vivo Insights of Small Vessel Changes with Age Using Ultra-Small-Superparamagnetic-Iron-Oxide (USPIO)-Enhanced MRI
This proposal seeks to perform an observational study for developing a new imaging tool using an ultra-small-superparamagnetic-iron-oxide (USPIO) contrast agent to characterize age-related microvascular changes ...Phase N/A Non-Interventional
-
Prevalence and predictors of antineuronal antibody positivity in focal epilepsy
This study aims to determine how often patients with focal epilepsy carry antibodies targeting brain proteins, and when it occurs, what the associated clinical features ...Phase N/A Non-Interventional
-
Behavioral and Neural Correlates of Speech Production during Delayed Auditory Feedback in Subthalamic Nucleus: A Prospective Study in Parkinson s Subjects Undergoing Deep Brain Stimulation Surgery
The purpose of this study is to find out the role of different brain structures in the in the motor control of speech. Additionally, this ...Phase N/A Non-Interventional
-
Mobilis Laboratory Subject Registry
The Mobilis Laboratory Subject Registry is a tool used to recruit healthy individuals and those with stroke for IRB-approved studies. The Registry will include circumscribed ...Phase N/A Non-Interventional
-
A SINGLE-CENTER OBSERVATIONAL LONGITUDINAL STUDY ON THE EFFECT OF SLOW WAVE SLEEP (SWS) CHARACTERISTICS AND RACE AND ETHNICITY ON AMYLOID BURDEN (A MARKER OF ALZHEIMER S DISEASE RISK) AMONG COGNITIVELY NORMAL ELDERLY.
African-Americans (AAs) have an increased prevalence of both Alzheimer’s disease (AD) and vascular risk factors for AD such as diabetes and hypertension when compared ...Phase N/A Interventional
-
Anti-Viral Therapy in Alzheimer's Disease
This study is being conducted to evaluate if the generic anti-viral medication, valacyclovir, is helpful in treating Alzheimer’s disease in patients who have tested ...Phase
Interventional
-
THE ROLE OF THE MICROBIOME IN MONOZYGOTIC TWINS WITH PSORIASIS AND PSORIATIC ARTHRITIS
We propose a longitudinal study of monozygotic twins discordant for psoriatic disease. Subjects will be characterized with detailed clinical questionnaires in addition to blood, fecal ...Phase N/A Non-Interventional
