Displaying 438 (all) recruiting clinical trials.
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Photobiomodulation Therapy Using the MuReva Phototherapy System to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Patients with Head and Neck Cancer Receiving Concurrent Radiation and Chemotherapy
The overall purpose of this clinical study is to evaluate safety and efficacy of the MuReva Phototherapy System with a light delivery mouthpiece to reduce ... -
A multipart exploratory study to evaluate splenic nerve stimulation in patients with rheumatoid arthritis.
The purpose of this research study is to test an investigational device and its accessories to help determine whether this study device may be used ... -
A Phase 1 Open-label Preliminary Pharmacokinetics (PK) and Safety Study of CLN-049 (An fms-like tyrosine kinase 3 [FLT3] x cluster of differentiation 3 [CD3] bispecific T cell engager) in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)
The purpose of the study is to determine the safety and tolerability of intravenous (IV) administered CLN-049. CLN-049 is a novel BITE therapy that target ... -
A Single-Center Observational Study of Targeted Muscle Reinnervation in Amputees
The purpose of this study is to follow the course of treatment and recovery of patients amputation, with and without targeted muscle reinnervation (TMR). Participating ... -
A pilot proof of concept study of the Effects of Administration of SCFA in Rheumatoid Arthritis (EASi-RA)
The purpose of this research is to study the effects of administering an oral short chain fatty acid (SCFA) dietary supplement along with methotrexate as ... -
Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations
The purpose of this study is to determine if a protein called fibroblast growth factor-2 (FGF-2) can be safely put on the eardrum and help ... -
Patient Expectations Following Flexor Tendon Repair
The purpose of this research study is to examine what patients expect to experience following surgical repair of a flexor tendon injury. Recovery from a ... -
Elucidating Neural Mechanisms and Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder
The purpose of this research study is to understand to how Mindfulness-Based Stress Reduction (MBSR)compared to a Stress Education (SE) class works for patients ... -
An Interventional Multi-Center investigation of Single Level Transforaminal Lumber Interbody Fusion (TLIF) Stabilized with Pedicle Screws
This research study is being conducted to collect data on the safety and effectiveness of a transforaminal lumbar interbody fusion (TLIF) procedure. This is the ... -
A Phase 3 Multi-center Randomized Double-blinded Study of MK-7684 with Pembrolizumab as a Co-formulation (MK-7684A) Versus Pembrolizumab Monotherapy as a First Line Treatment for Participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung Cancer
The purpose of the study is to determine and compare MK-7684A to pembrolizumab alone for participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung ...