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A pragmatic trial to evaluate the intermediate-term effects of early aggressive versus escalation therapy in people with multiple sclerosis
The purpose of this research is to identify the most appropriate treatment strategy for people with multiple sclerosis (MS), especially shortly after diagnosis when it ...Phase N/A
Interventional
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In vivo insights of small vessel changes with age using ultra-small-superparamagnetic-iron-oxide (USPIO)-enhanced MRI
The purpose of this research study is to investigate a new magnetic resonance imaging (MRI) method that could provide new fundamental insights to a more ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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i-Matter: Investigating an mHealth texting tool for embedding patient-reported data into diabetes management
This study has two phases that will be completed over the course of 5 years. Phase 1 consists of the following: (1) focus groups to ...Phase
Interventional
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A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis
This study will examine subjects with biliary cholangitis (PBC) which is a chronic, or long-term, disease of the liver characterized by damaged bile ducts due ...Phase N/A Non-Interventional
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Prevalence and predictors of antineuronal antibody positivity in focal epilepsy
Antibodies are proteins that normally exist to fight off things foreign to your body (like infections), but in certain diseases, they can attack the body ...Phase N/A Non-Interventional
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Behavioral and Neural Correlates of Speech Production during Delayed Auditory Feedback in Subthalamic Nucleus: A Prospective Study in Parkinson s Subjects Undergoing Deep Brain Stimulation Surgery
The purpose of this study is to find out the role of different brain structures in the motor control of speech. Additionally, this study will ...Phase N/A Non-Interventional
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An Observational Study of Patients Undergoing Therapy for Chronic Hepatitis B (HBV) Infection
The TARGET-HBV study engages an observational research design to conduct a comprehensive review of therapeutic outcomes for patients with chronic hepatitis B (HBV) who are ...Phase N/A Non-Interventional
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Mobilis Laboratory Subject Registry
The purpose of this study is to develop a resource that researchers can use to recruit healthy individuals and patients with stroke in IRB-approved studies ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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A Single-Center Observational Longitudinal Study on the Effect of Slow Wave Sleep (SWS) Characteristics and Race and Ethnicity on Amyloid Burden (A Marker of Alzheimer s Disease Risk) among cognitively normal elderly
Sleep AWARE is a research study funded by the National Institutes of Health and the National Institutes for Aging. We will examine how race, genes ...
Phase N/A Interventional
Accepts Healthy Volunteer
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Anti-viral therapy in Alzheimer's disease
This study is being conducted to evaluate if the generic anti-viral medication, valacyclovir, is helpful in treating Alzheimer's disease in patients who have tested positive ...Phase
Interventional
