Displaying 507 (all) recruiting clinical trials.
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VEDOKIDS study: Predicting response to Vedolizumab in Pediatric Inflammatory Bowel Diseases including drug levels: a multi-center prospective Pan- European cohort study (P-ECCO and ESPGHAN)
Vedolizumab (VDZ) is a humanized immunoglobulin G1 monoclonal antibody acting against a4ß7 integrin which modulates lymphocyte trafficking in the gut. Results from the adult GEMINI-1 ...Phase N/A
Non-Interventional
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Site for A Multi-Center Prospective Randomized Controlled Trial Comparing the Safety and Effectiveness of prodisc C SK and prodisc C Vivo to Mobi-C Cervical Disc in the Treatment of Two-Level Symptomatic Cervical Disc Disease (SCDD)
Research study to evaluate the safety and effectiveness of prodisc C SK and prodisc C Vivo versus Mobi-C (currently available on market).Phase
Interventional
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Microbial and human biomarkers of thoracic disease after lung transplantation
We will prospectively collect airway and blood samples on 200 subjects undergoing lung transplantation. We will evaluate airway microbial signatures associated with local (lower airway ...Phase N/A Non-Interventional
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Multi-Center Prospective Evaluation of Complex Adult Spinal Deformity Surgery (CADS)
The goal of this study is to evaluate surgical treatment outcomes of complex adult spinal deformity patients, including radiographic and clinical outcomes, surgical and postoperative ...Phase N/A Non-Interventional
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New onset refractory status epilepticus (NORSE)
This is a multi-site study aiming at creating a biorepository of a rare disease, new onset refractory status epilepticus (NORSE), to establish clinical characteristics, outcomes ...Phase N/A Non-Interventional
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WUH: COG# AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
?Despite recent improvements in outcome for children with newly diagnosed high-risk neuroblastoma, cure rates remain unsatisfactory. Further, these gains have been the result of interventions ...Phase
Interventional
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Study of inherited monogenic disorders in patient and tissue-specific cells
We propose to collect blood samples to reprogram into patient-specific neuronal, cardiac, and cancer cell lines (see below in the background section) from patients diagnosed ...Phase N/A Non-Interventional
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Single-Center Pilot Study of Living Donor Kidney Transplant from HIV-positive Donor to HIV-positive Recipient
This study will evaluate the feasibility and safety of living donor kidney transplant from an HIV-infected donor to an HIV-infected recipient.Phase N/A Non-Interventional
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A single-center observational study of the natural history and pathogenesis of hidradenitis suppurativa
A single-center observational study of the natural history and pathogenesis of hidradenitis suppurativaPhase N/A Non-Interventional
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A 12-week randomized double-blind placebo-controlled trial investigating the effects of Levetiracetam in early psychosis
This is a 12-week study of levetiracetam in conjunction with a second generation antipsychotic in early psychosis patients with treatment-resistant symptoms. Treatment with antipsychotics has ...Phase
Interventional
