Displaying 86 (all) recruiting clinical trials.
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C5041018 A PHASE 2 OPEN LABEL SINGLE ARM STUDY TO EVALUATE THE EFFICACY PHARMACOKINETICS AND SAFETY OF ETRASIMOD IN PEDIATRIC PARTICIPANTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS
The purpose of this study is to assess the effects of the study drug, etrasimod, for treating pediatric ulcerative colitis (UC) participants. Participants will take ...Phase
Interventional
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Phase III trial of radiotherapy followed by adjuvant temozolomide in combination with the IDH inhibitor vorasidenib vs. placebo in IDH-mutated newly-diagnosed grade 3 astrocytoma
This is a Phase III study for people with newly diagnosed grade 3 astrocytoma that has a mutation in the IDH (mIDH) gene. All participants ...
Phase
Interventional
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A Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for HOPE Patients with Hematologic Malignancies or Disorders
This in an expanded access program (EAP) to provide donor bone marrow to patients meeting eligibility criteria as well as safety in its use as ...Phase N/A Interventional
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RLY-2608-201: A Phase 2 Study of Mutant-selective PI3Ka Inhibitor RLY-2608 in Adults and Children with PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation
The purpose of this study is to learn about the safety and efficacy of RLY-2608 when given to individuals who have been diagnosed with PIK3CA ...Phase
Interventional
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A Modular Phase I/II Open-label Multicentre Study to Evaluate the Safety Tolerability and Efficacy of AZD3470 a PRMT5 Inhibitor as Monotherapy and in Combination With Anticancer Agent(s) in Participants With Relapsed/Refractory Haematologic Malignancies
This is a Phase I/II, open-label, multicentre clinical study that is testing AZD3470, an investigational oral medicine, in people with blood cancers (haematologic malignancies ...
Phase
Interventional
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Building a multidisciplinary transition readiness clinic for adolescents and young adults with inflammatory bowl disease using the TRAQ
The purpose of this study is to evaluate a structured transition program for adolescents and young adults with inflammatory bowel disease (IBD) at the NYU ...Phase N/A
Non-Interventional
