Displaying 671 (all) recruiting clinical trials.
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MAGNITUDE: A Phase 3 Multinational Multicenter Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants with Transthyretin Amyloidosis with Cardiomyopathy (ATTR-CM)
This trial is recruiting patients with a condition known as Transthyretin (TTR) Amyloidosis with Cardiomyopathy or ATTR-CM. In individuals with this condition, the heart muscle ... -
A Phase 2 Open Label Study of REC-4881 in Participants with Unresectable Locally Advanced or Metastatic Cancer with AXIN1 or APC Mutation
This is a multi-center, open-label study to investigate the safety, efficacy and pharmacokinetics of REC-4881 (12 mg PO daily doses) for the treatment of participants ... -
The (IRAD) International Registry for Acute Aortic Dissection
The purpose of this study is to collect information regarding your medical condition for a registry. The aim of the registry is to document a ... -
A SINGLE-CENTER OBSERVATIONAL STUDY OF PAIN PHENOTYPES IN PSORIATIC ARTHRITIS
This study is an observational study of individuals with psoriatic arthritis (PsA) to define types of pain. We aim to better understand the prevalence of ... -
Time to Union: A Comparison of the Medartis Scaphoid Volar Locking Plate and Headless Compression Screws for Treatment of Scaphoid Nonunion
The purpose of this study is to determine the optimal approach for treating scaphoid nonunions surgically. A scaphoid nonunion occurs when you have a fractured ... -
Microbial and Host Biomarkers for Endotyping Venous Thromboembolism Patients
This research aims to understand the differences between blood clotting caused by viruses affecting the whole body versus those affecting the lungs, and how different ... -
A single-center observational longitudinal study to monitor skeletal muscle aging with quantitative MRI
The muscles in your legs and shoulders change as you get older and they become weaker. The purpose of this study is to investigate new ... -
A Phase III Randomized Double-Blind Placebo-Controlled Multicenter Global Study of Rilvegostomig in Combination With Chemotherapy as Adjuvant Treatment After Resection of Biliary Tract Cancer With Curative Intent (ARTEMIDE-Biliary01)
A global study to assess the efficacy and tolerability of rilvegostomig compared to placebo in combination with investigator's choice of chemotherapy in participants with ... -
METRO Lupus Consortium
The purpose of this study is to learn more about patients with lupus ("systemic lupus erythematosus" or "SLE") who may have injury to their kidney ... -
AN OPEN-LABEL MULTICENTER PHASE 1/2 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF AB-2100 IN PATIENTS WITH RECURRENT ADVANCED OR METASTATIC CLEAR-CELL RENAL CELL CARCINOMA (CCRCC)
This is a study seeing if a new cellular medicine called AB-2100, a logic-gated CAR T cell targeting PSMA and Ca-IX, is effective for adult ...