Displaying 658 (all) recruiting clinical trials.
-
Type 1 Diabetes Pathway to Prevention Study (Natural History) Study
The goals of the TrialNet Pathway to Prevention Study are to gain information about the pathogenesis and natural history of type 1 diabetes (T1D), and ...Phase N/A
Non-Interventional
-
Metabolomics of World Trade Center-Lung Injury: Biomarker Validation Assessment and Dietary Intervention: Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial
This is a dietary intervention study that will examine the therapuetic effect of a Calorie Restricted Mediterranean (LoCalMed) diet on clinical endpoints such as FEV1 ...Phase N/A Non-Interventional
-
ADAPTATION TO FREQUENCY-PLACE FUNCTIONS IN COCHLEAR IMPLANT USERS
It is a basic study that will examine adaptation to frequency-place maps in cochlear implant users. The main outcome measures will be measures of speech ...Phase N/A Non-Interventional
-
Auditory Pathway Mapping in Pediatric Patients with Sensorineural Hearing Loss Being Evaluated for Surgical Therapy
The objective of this study is to develop methods for in vivo MRI detection of abnormal cochlear nerve and auditory brainstem pathway pathology that will ...Phase N/A Non-Interventional
-
Mechanisms of Vascular Aneurysms
Our mission is to enable the use of human tissues with outcome data by basic and clinical investigators for research into the biology, causes, prevention ...Phase N/A Non-Interventional
-
Genetic evaluation of patients with undiagnosed diseases
The purpose of this study is to use extensive sequencing of the DNA (genetic material inherited from parents) or RNA (transcripts of the DNA), and ...Phase N/A Non-Interventional
-
Impact of time restricted feeding in obese subjects undergoing a low-calorie diet
The impact of circadian rhythms appear to impact various biologic mechanisms including sleep, nutrition, and physical activity. We wish to understand the impact of timing ...Phase N/A
Interventional
-
Multicenter Study of Epilepsy Surgery Long Term Outcomes Mortality
The Multicenter Study of Epilepsy Surgery – Long Term Outcomes Mortality study aims to examine the various aspects of epilepsy surgery outcomes after more than 10 ...Phase N/A Non-Interventional
-
A Phase 2 Randomized Study of Adjuvant Immunotherapy With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab Versus Pembrolizumab Alone After Complete Resection of High-Risk Melanoma (mRNA-4157-P201)
This is an open-label, randomized, Phase 2 study. Approximately 150 eligible patients will be randomly assigned in a 2:1 ratio to the combination arm ...Phase
Interventional
-
SWIFT TRIAL: SURGICAL WEIGHT-LOSS TO IMPROVE FUNCTIONAL STATUS TRAJECTORIES FOLLOWING TOTAL KNEE ARTHROPLASTY
We will compare long-term outcomes in the test and control arms of the study. These outcomes will include measures of physical function, mobility, indices of ...Phase N/A Interventional
