Displaying 671 (all) recruiting clinical trials.
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A Proof-of-Concept Study to Assess the Efficacy Safety and Tolerability of itepekimab (anti-IL-33 mAb) in Participants with Non-Cystic Fibrosis Bronchiectasis
This study aims to evaluate the safety, efficacy, and tolerability of itepekimab in patients with bronchiectasis, in addition to their current treatment regimen, which may ...Phase
Interventional
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A Phase 1a/1b First-in-human Multicenter Study to Assess the Efficacy and Safety of RGT-61159 for Treatment of Patients with Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)
This study will test the potential tumor-fighting effects of a daily medication called RGT-61159 for patients with advanced ACC or CRC, two types of cancer ...
Phase
Interventional
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Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults with Severe Hypertriglyceridemia (SHASTA-3 Study)
The purpose of this research study is to look at how safe and effective ARO-APOC3 is at lowering triglycerides in people with severe hypertriglyceridemia. Hypertriglyceridemia ...Phase
Interventional
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A randomized phase 3 open-label study to evaluate SGN-B6A compared with docetaxel in adult subjects with previously treated non-small cell lung cancer
This is a study for adult patients who had lung cancer (specifically NSCLC or non-small cell lung cancer) before and are going to try two ...
Phase
Interventional
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Randomized Clinical Evaluation of the AccuCinch Ventricular Restoration System in Patients who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)
The purpose of this research study is to assess the safety and effectiveness of the AccuCinch Ventricular Restoration System and compare it to standardized heart ...Phase
Interventional
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The Prospective Natural History of Congenital Insensitivity to Pain with the Anhidrosis (CIPA)
The purpose of this study is to create a database of clinical information collected from you/your child’s medical chart on a yearly basis ...Phase N/A
Non-Interventional
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RASolute 302: A Phase 3 Multicenter Open-label Randomized Study of RMC-6236 versus Investigator s Choice of Standard of Care Therapy in Patients with Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
This study is being done to find out if the treatment RMC-6236 can help patients with advanced pancreatic cancer live longer or keep their cancer ...
Phase
Interventional
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PHINDER: Pulmonary Hypertension Screening in Patients with Interstitial Lung Disease for Earlier Detection
The PHINDER study is a research study that will collect data to better understand screening for pulmonary hypertension (PH). The goal is to use the ...Phase N/A Non-Interventional
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Study of newly identified natriuretic protein haptoglobin related protein without signal peptide as biomarker for renal salt wasting and new syndrome of renal salt wasting in Alzheimer s disease: Study to identify protein that alters brain cell function in Alzheimer s disease
This study is being done to better understand hyponatremia (low blood sodium). We have now identified a protein that may be used to diagnose a ...Phase N/A Interventional
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DOUBLE-BLIND PLACEBO-CONTROLLED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PLOZASIRAN IN ADULTS WITH HYPERTRIGLYCERIDEMIA (MUIR-3 STUDY)
The purpose of this research study is to look at how safe and effective ARO-APOC3 is at lowering triglycerides in people with hypertriglyceridemia. Hypertriglyceridemia is ...Phase
Interventional
