Displaying 658 (all) recruiting clinical trials.
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A Phase 2 Randomized Placebo-controlled Parallel Group Multicenter 12-week Study with a 52-week Extension to Evaluate the Efficacy and Safety of Two Doses of K-808 (Pemafibrate) in Subjects with Primary Biliary Cholangitis with Inadequate Response to Ursodeoxycholic Acid and/or Obeticholic Acid Treatment
This study will look at a study drug, called K-808, for participants with a liver condition called primary biliary cholangitis (PBC).
PBC is defined by ...Phase
Interventional
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Assessment of Functional Recovery of Adults who Sustain Brachial Plexus Injuries
The purpose of this study is to evaluate the range of motion improvements of patients receiving surgical and nonsurgical treatment for proximal humerus fractures, brachial ...Phase N/A
Non-Interventional
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SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Moderately to Severely Active SLE
The purpose of this program is to assess the safety and efficacy of upadacitinib compared with placebo (fake drug) for the treatment of signs and ...Phase
Interventional
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A Phase 3 Superiority Study Comparing the Safety and Efficacy of SNP-ACTH (1-39) Gel compared to Rituximab and FDA approved biosimilars in Adults with Primary Membranous Nephropathy (PMN) in a Two-Phase Adaptive Trial Design
This trial is recruiting individuals with Primary Membranous Nephropathy (PMN) - a kidney-specific, autoimmune disease in which your body's defense system turns against you and ...Phase
Interventional
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ALXN2220-ATTRCM-301: A Phase 3 Randomized Double-blind Placebo-controlled Multicenter Study to Evaluate the Efficacy and Safety of Amyloid Depleter ALXN2220 in Adult Participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
We are doing this study to learn more about an experimental drug called ALXN2220 for the proposed treatment of adult patients with ATTR-CM, and to ...Phase
Interventional
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SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Moderately to Severely Active SLE
The purpose of this research study is to assess the safety and efficacy of upadacitinib compared with placebo (fake drug) for the treatment of signs ...Phase
Interventional
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A Phase 1 Randomized Observer-Blind Dose-Ranging Study To Evaluate The Safety Tolerability And Immunogenicity Of Modified RNA Vaccine Candidates Against Pandemic Influenza In Healthy Adults
This vaccine trial will evaluate the safety, tolerability, and effectiveness of an investigational vaccine against bird flu, also known as Avian Influenza or H5N1 virus ...Phase
Interventional
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An observational multi-center study to validate outcome measures for future clinical trials of Multiple System Atrophy (MSA)
The purpose of this research study is to develop and validate new methods to measure if a potential drug being tested in future clinical trials ...Phase N/A Non-Interventional
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Prospective Cohort Registry of Patients with Inflammatory Bowel Disease and Overlap Spondyloarthritis
The purpose of this research study is to use two questionnaires to identify patients who have both inflammatory bowel disease and spondyloarthritis and to then ...Phase N/A Interventional
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A Prospective Multicenter Randomized Two-Arm Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch Sirolimus-Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis (MAGICAL ISR)
The treatment for narrowed or blocked arteries often involves stents, which are inserted into heart blood vessels to alleviate blockages. Drug-eluting stents (DES) release medication ...Phase
Interventional
