Displaying 671 (all) recruiting clinical trials.
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A Prospective Observational Sub-Study of the Global Hypophosphatasia Registry to Describe the Potential Risk of Immune-Mediated Loss of Pharmacological Effect of Asfotase Alfa in Participants with Hypophosphatasia (HPP)
This study collects observational Standard of Care (SOC) data in patients currently receiving asfotase alfa or about to start treatment with asfotase alfa as determined ...Phase N/A
Non-Interventional
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Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Collection Protocol: The NYU Children's Health and Environment Study (NYU CHES) ECHO Cohort Study Site
ECHO is a nationwide research program whose mission is to enhance the health of children for generations to come.The goal is to learn how ...Phase N/A Non-Interventional
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A Phase II Clinical Trial of Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence
This study is designed to test a treatment called STK-012 for patients with advanced solid tumors. It is an open-label trial, meaning both the researchers ...
Phase
Interventional
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A Proof-of-Concept Study to Assess the Efficacy Safety and Tolerability of itepekimab (anti-IL-33 mAb) in Participants with Non-Cystic Fibrosis Bronchiectasis
This study aims to evaluate the safety, efficacy, and tolerability of itepekimab in patients with bronchiectasis, in addition to their current treatment regimen, which may ...Phase
Interventional
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A Phase 1a/1b First-in-human Multicenter Study to Assess the Efficacy and Safety of RGT-61159 for Treatment of Patients with Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)
This study will test the potential tumor-fighting effects of a daily medication called RGT-61159 for patients with advanced ACC or CRC, two types of cancer ...
Phase
Interventional
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Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults with Severe Hypertriglyceridemia (SHASTA-3 Study)
The purpose of this research study is to look at how safe and effective ARO-APOC3 is at lowering triglycerides in people with severe hypertriglyceridemia. Hypertriglyceridemia ...Phase
Interventional
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A randomized phase 3 open-label study to evaluate SGN-B6A compared with docetaxel in adult subjects with previously treated non-small cell lung cancer
This is a study for adult patients who had lung cancer (specifically NSCLC or non-small cell lung cancer) before and are going to try two ...
Phase
Interventional
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Randomized Clinical Evaluation of the AccuCinch Ventricular Restoration System in Patients who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)
The purpose of this research study is to assess the safety and effectiveness of the AccuCinch Ventricular Restoration System and compare it to standardized heart ...Phase
Interventional
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The Prospective Natural History of Congenital Insensitivity to Pain with the Anhidrosis (CIPA)
The purpose of this study is to create a database of clinical information collected from you/your child’s medical chart on a yearly basis ...Phase N/A Non-Interventional
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RASolute 302: A Phase 3 Multicenter Open-label Randomized Study of RMC-6236 versus Investigator s Choice of Standard of Care Therapy in Patients with Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
This study is being done to find out if the treatment RMC-6236 can help patients with advanced pancreatic cancer live longer or keep their cancer ...
Phase
Interventional
