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PBM-LEF Study: The Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients: A Pilot Study
This study is testing if LED light therapy, called photobiomodulation (PBM), can help reduce tissue swelling and scarring in the neck area for head and ...
Phase
Interventional
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Randomized Phase II Clinical Trial of Olaparib + Pembrolizumab vs. Olaparib Alone as Maintenance Therapy in Metastatic Pancreatic Cancer Patients with Germline BRCA1 or BRCA2 Mutations
chemotherapy. The goals of the study are to check how safe and well-tolerated both treatments are, how long people stay without their cancer getting worse ...
Phase
Interventional
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VECTOR-HF IIb: a multi-center national open label single-arm prospective clinical study to evaluate the safety usability and performance of the V-LAP system
The purpose of this study is to evaluate whether the V-LAP™ system is safe, and to assess its performance in obtaining left atrial pressure measurement ...Phase
Interventional
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A Phase II Single-Arm Study of Craniospinal Irradiation with Linac Based Volumetric Modulated Arc Therapy (VMAT) for Patients with Leptomeningeal Metastasis
This study is a non-randomized phase II single-institution trial in which patients who consent to the trial will be treated with linac based VMAT CSI ...Phase
Interventional
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A Multi-centered Double-blind Randomized Placebo-controlled Parallel Group Phase 2 Study of TEV-56286 for the Treatment of Patients with Multiple System Atrophy
The study is evaluating the safety and effectiveness of "TEV-56286" to treat multiple system atrophy (MSA).
The total duration of participation is just over one ...Phase
Interventional
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A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics Pharmacokinetics Safety and Tolerability of REGN7544 an NPR1 Antagonist Monoclonal Antibody in Patients with Postural Orthostatic Tachycardia Syndrome
The purpose of this research study is to research an experimental drug called REGN7544. The study is focused on participants with postural orthostatic tachycardia syndrome ...Phase
Interventional
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A Phase 2 Randomized Double-Blind Placebo-Controlled Dose-Ranging Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults with Cutaneous Sarcoidosis
The purpose of this clinical research study is to learn more about the use of an investigational medicine, called brepocitinib, for the treatment of adults ...Phase
Interventional
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A pivotal prospective multicentre single-arm study evaluating the safety and efficacy of a dexamethasone eluting Slim Modiolar electrode array (EA32D)
The purpose of this study is to test a new type of cochlear implant called the Cochlear™ Nucleus® CI632D cochlear implant including a Slim Modiolar ...Phase
Interventional
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A Phase 2 Open-label Randomized Study of V940 in Combination With BCG Versus BCG Monotherapy in Participants With High-risk Non-muscle Invasive Bladder Cancer (INTerpath-011)
This study is designed to compare the antitumor activity of V940 in combination with BCG to BCG monotherapy, and evaluate safety of both treatments, in ...Phase
Interventional
