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A Randomized Double-Blind Placebo-Controlled Phase 3 Study of AKCEA-APOCIII-LRx Administered Subcutaneously to Patients with Familial Chylomicronemia Syndrome (FCS)
The purpose of this research study is to see if an investigational drug known as ISIS 678354 may help lower the risk of developing pancreatitis ...Phase
Interventional
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Genentech- CA41705 - new study CDA
The purpose of this study is to compare the effects, good or bad, of the study drug called obinutuzumab (also known as Gazyva or Gazyvaro ...Phase
Interventional
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An INS1007 Phase III program in Non Cystic Fibrosis Bronchiectasis
The purpose of this study is to evaluate the efficacy, safety, and tolerability of brensocatib as treatment for non-cystic fibrosis bronchiectasis (NCFBE). Brensocatib is an ...Phase
Interventional
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ENCORE - A Randomized Double-Blind Placebo-Controlled Active Comparator Multicenter Study to Evaluate the Efficacy and Safety of an Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) treatment on patient-reported symptoms in patients newly ...Phase
Interventional
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AALL1631: International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ ALL Testing Imatinib in Combination with Two Different Cytotoxic Chemotherapy Backbones
The purpose of the study is to determine how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive ...Phase
Interventional
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A Phase 3 Prospective Multicenter Double-Blind Randomized Placebo Controlled Study to Evaluate the Efficacy of Amniotic Suspension Allograft (ASA) in Patients with Osteoarthritis of the Knee
The purpose of this clinical research study is to learn more about the use of the study drug, amnion suspension allograft (written as ‘ASA’ in ...Phase
Interventional
Accepts Healthy Volunteer
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Phase 3 Clinical Trial in Adult Growth Hormone Deficiency with TransCon hGH
The primary objective of this trial is to assess the efficacy of once-weekly lonapegsomatropin compared to placebo in adults with growth hormone deficiency (GHD). The ...Phase
Interventional
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A Randomized Controlled Trial to compare the effectiveness of Fecal Microbiota Transplantation (FMT) in combination with Bezlotoxumab compared to FMT and placebo for the prevention of CDI recurrence in patients with Inflammatory Bowel Disease and Recurrent Clostridium difficile Infection
This study will find out if fecal microbiota transplantation (also known as FMT) paired with Bezlotoxumab compared to FMT and placebo is a better treatment ...Phase
Interventional
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Optimizing Retention Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
This multicenter study seeks to better evaluate treatment strategies for the management of opioid use disorder – it aims to improve treatment outcomes for both patients ...Phase
Interventional
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ASSURE: An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC)
The purpose of this research study is to evaluate the long-term safety and tolerability of seladelpar in treating PBC patients. Primary Biliary cholangitis (PBC) is ...Phase
Interventional
