Displaying 555 (all) recruiting clinical trials.
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Interventional randomized double-blind placebo-controlled optional open-label extension trial of Lu AF82422 in participants with Multiple System Atrophy.
The purpose of this trial is to investigate whether Lu AF82422 is safe and effective in treating patients with multiple system atrophy (MSA). This trial ...Phase
Interventional
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A Phase III Randomised Double-blind Placebo-controlled Event-driven Study to Assess the Efficacy Safety and Tolerability of Baxdrostat in Combination with Dapagliflozin Compared with Dapagliflozin Alone on Renal Outcomes and Cardiovascular Mortality in Participants with Chronic Kidney Disease and High Blood Pressure
The purpose of this study is to investigate the efficacy, safety and tolerability of baxdrostat in combination with dapagliflozin, compared with placebo and dapagliflozin intreating ...Phase
Interventional
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EXpanding Prenatal cell free DNA screening Across moNogenic Disorders (EXPAND)
The purpose of this study is to develop an investigational non-invasive prenatal genetic screening test that will assess a baby’s risk of being affected ...Phase N/A
Non-Interventional
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A Global Randomized Open-label Multicenter Phase 2b/3 Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1)
The main goal of this study is to determine the effectiveness of BJT-778 as a long-term treatment in patients with hepatitis delta virus (HDV) infection.Phase
Interventional
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A Phase 1 Open-Label Multicenter Study of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
To evaluate the safety, tolerability, and DLTs and determine the MTD and/or RDE(s) of INCA33890 in participants with select advanced or metastatic solid ...Phase
Interventional
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A Phase 1 First in Human Randomized Placebo-controlled Trial with a Controlled Gluten Challenge to Evaluate Safety Tolerability Pharmacokinetics and Pharmacodynamics of VTP-1000 in Adults with Celiac Disease
The purpose of this research study is to test a possible new treatment for celiac disease called VTP 1000.Phase
Interventional
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The Impact of Cardiac Rehabilitation on Heart Failure Self-care Maintenance
The purpose of this study is to explore the impact of cardiac rehabilitation (CR) on heart failure self-care maintenance and to identify predictors of CR ...Phase N/A Non-Interventional
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A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients with Refractory Advanced/Metastatic Microsatellite Stable Colorectal Cancer
This is a Phase 2 study testing whether a combination of TAS-102 and fruquintinib (a selective oral kinase inhibitor) is more effective and safer than ...
Phase
Interventional
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A phase 1 placebo-controlled dose-escalation study of the safety pharmacokinetics and antiviral activity of a potent neutralizing monoclonal antibody in individuals with chronic hepatitis B infection
The purpose of this research study is to evaluate the safety and tolerability of intravenous (through a vein in your arm) infusions of a new ...Phase
Interventional
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Stress and Anxiety Effects on Valuation
The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes.
This study will enroll healthy volunteers ...Phase N/A Interventional
