Displaying 648 (all) recruiting clinical trials.
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Post-Cardiopulmonary Bypass Vasoplegia: Cytokine/Chemokine/Immunotranscriptomic Causes or Consequences
All patients undergoing open heart surgery with the utilization of cardiopulmonary bypass (CPB) are at risk for developing varying degrees of vasoplegia. Although a precise ...Phase N/A
Non-Interventional
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Reinforcement Learning and Attention in Decision Making
Reinforcement effects are a tenet of human decision-making under uncertainty, according to which people increase their risk-taking following a gain and decrease their risk-taking following ...Phase N/A Non-Interventional
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A Phase 2a Multicenter Randomized Doubleblind Study Evaluating the Efficacy and Safety of Subcutaneously Administered combination therapy in Improving the Signs and Symptoms in Participants with Active Psoriatic Arthritis.
This is a Phase 2a randomized, double-blind, active-controlled, parallel-group, multicenter, proof-of-concept (POC) clinical study designed to evaluate the efficacy and safety of combination therapy with ...Phase
Interventional
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Epigenetic Characterization of Immune Cells in Parkinson s disease and Prodromal Stages
Inflammation is one of the pathogenic mechanisms implicated in PD. To assess the activation and differences in regulation of the gene expression machinery in pre-motor ...Phase N/A Non-Interventional
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Parkinson s Foundation PD GENEration Genetic Registry
The Parkinson’s Foundation PDGENEration Genetic Registry study is a prospective registry study of people who are clinically diagnosed with PD. The participants will consist ...Phase N/A Non-Interventional
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A Follow-Up Open-Label Research Evaluation of Sustained Treatment with Aficamten (CK-3773274) in Hypertrophic Cardiomyopathy (HCM)
This is an open-label study of CK-3773274 in patients with HCM. The treatment duration is anticipated to be multiple years, concluding when marketing authorization is ...Phase
Interventional
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Role of the Decision-Making Reference Point in Cognition and Psychopathology
Mood disorders are characterized by a tendency to subjectively evaluate objectively positive outcomes in a negative light. A fundamental feature of nearly all standard models ...Phase N/A Non-Interventional
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Technical development observational study for novel MRI acquisition and reconstruction strategies
The objective of this study is to determine whether new advanced engineering techniques used at fields up to 7T can produce meaningful quantitative, structural, physiological ...Phase N/A Non-Interventional
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US Pilot Study to Evaluate the Safety and Effectiveness of the CereVasc eShunt System in the Treatment of Normal Pressure Hydrocephalus
The eShunt System is intended to shunt cerebrospinal fluid from the intracranial subarachnoid space to the venous system for the treatment of patients with normal ...Phase N/A Interventional
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A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED MULTICENTER OUTPATIENT PARALLEL-GROUP STUDY TO ASSESS THE EFFICACY AND SAFETY OF STACCATO ALPRAZOLAM IN PARTICIPANTS 12 YEARS OF AGE AND OLDER WITH EPILEPSY WITH A PREDICTABLE SEIZURE PATTERN.
Staccato alprazolam is being developed for the indication of rapid cessation of a prolonged focal or generalized seizure that has not progressed to status epilepticus ...Phase
Interventional
