Displaying 664 (all) recruiting clinical trials.
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TH-189: A Phase 2 Study of Nivolumab plus Ramucirumab in Patients with Recurrent Advanced Metastatic Non-Small Cell Lung Carcinoma
The study will enroll patients with prior IO therapy (alone or in combination with chemotherapy or in combination with other IO agents) regardless of the ...Phase
Interventional
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A Phase 2b Randomized Double-blind Placebo-controlled Multi-center Study of the Effects of Psilocybin-assisted Psychotherapy on Psychiatric and Existential Distress in Advanced Cancer
This trial is designed to evaluate efficacy and psychological mechanisms of single-dose psilocybin-assisted psychotherapy (PAP) to treat psychiatric (anxiety, depression) and existential distress (demoralization, death ...Phase
Interventional
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A Phase I Study of ExoFlo an ex vivo Culture-expanded Adult Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product for the Treatment of Medically Refractory Ulcerative Colitis
Patients with Ulcerative Colitis are often managed with corticosteroids, immunomodulators and monoclonal antibodies, all fraught with potential side effects. The advent of the biologic era ...Phase
Interventional
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Integrated multi-omics approaches to precision medicine in kidney disease (iMAP-Kidney)
The primary objective of the study is to establish a biorepository (tissue bank) for the storage of plasma, serum, DNA, RNA, urine, and fresh tissue ...Phase N/A
Non-Interventional
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A Phase 2 Study of Darolutamide in Combination with Leuprolide Acetate in Hormone-Therapy Na ve Recurrent and/or Metastatic Androgen Receptor (AR) Positive Salivary Gland Cancer
A Phase 2 Study of Darolutamide in Combination with Leuprolide Acetate in Hormone-Therapy Naïve Recurrent and/or Metastatic Androgen Receptor (AR) Positive Salivary Gland CancerPhase
Interventional
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A Phase 3 Multi-center Randomized Withdrawal and Long-Term Extension Study of Ampreloxetine for the Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Participants with Multiple System Atrophy
To evaluate the efficacy and durability of ampreloxetine in participants with MSA and symptomatic nOH compared with placebo as measured by the OHSA composite score ...Phase
Interventional
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International study of Artificial Intelligence-based Diagnosis of Cardiomyopathy using Cardiac MRI
This study is testing the ability of artificial intelligence-based algorithms to look at cardiac MRI images to: i) decide what disease a patient has, and ...Phase N/A Non-Interventional
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Imaging the human eye using visible light Optical Coherence Tomography
We will perform non-invasive optical imaging of the retina in adult human subjects with a low power light beamPhase N/A Non-Interventional
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Post-Organ Transplant Housing Barriers: A Mixed-methods Observational Study of Patients who Received Non-Profit Assistance for Post-Transplant Housing
This study will administer surveys to and conduct interviews with patients who received post-transplant housing assistance from one of four organizations: the Heartfelt Help Foundation ...Phase N/A Non-Interventional
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A Multi-phase Dose-Escalation followed by an Open-label Randomized Crossover Study of Oral ASTX030 (Cedazuridine and Azacitidine Given in Combination) Versus Subcutaneous Azacitidine in Subjects with Myelodysplastic Syndromes (MDS) Chronic Myelomonocytic Leukemia (CMML) or Acute Myeloid Leukemia (AML)
Study ASTX030-01 is being conducted in subjects with myelodysplastic syndromes (MDS), MDS/myeloproliferative neoplasms (MPN) including chronic myelomonocytic leukemia (CMML), or acute myeloid leukemia (AML ...Phase
Interventional
