Displaying 667 (all) recruiting clinical trials.
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A pilot proof of concept study of the Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders (EASi-RAIR)
This study is a pilot, proof of concept study to determine the effects of administering an oral SCFA supplement to RA patients with inadequate response ...Phase
Interventional
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Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression R33
~60 subjects with MDD will undergo MRI scanning during t-PBM (administered with an irradiance of 291.7 mW/cm2 for 333s) before and after a ...Phase
Interventional
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A Phase 2b Double-Blind Placebo-Controlled Study to Evaluate Peresolimab in Adult Participants with Moderately-to-Severely Active Rheumatoid Arthritis
This study includes a . screening period . 12-week double-blind, placebo-controlled treatment period . 48-week double-blind treatment period, and . post-treatment follow-up. At Week 12, participants receiving placebo Q4W ...Phase
Interventional
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The Psorcast Study: A Validation Study of a Smartphone Sensor-Based Patient-Driven Detection of Psoriatic Disease
Smartphone-based and physician-assessed measures will be collected at baseline and 12 weeks after initiating a new therapy for psoriatic disease. Weekly digital assessments will also ...Phase N/A
Non-Interventional
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AERODIGESTIVE DISEASE IN THE WORLD TRADE CENTER EXPOSED FDNY COHORT: A Single Center Observational Study of Biomarkers of Airway Disease Barrett s and Underdiagnosed Reflux Noninvasively
The destruction of the World Trade Center (WTC) led to the exposure of thousands of first responders and inhabitants of New York City to WTC-particulate ...Phase N/A Non-Interventional
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Seeded Cells on Matrix Plug Treating Crohn's Perianal Fistulas (STOMP II)
A Phase II study to assess the safety and efficacy of AVB-114 in treatment of complex Crohn’s perianal fistulas in subjects with quiescent rectal ...Phase
Interventional
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A Multicenter Randomized Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of BIIB059 in Adult Participants With Active Systemic Lupus Erythematosus Receiving Background Non-Biologic Lupus Standard of Care
This is a multicenter, randomized, double-blind, placebo-controlled, Phase 3 study designed to evaluate the efficacy and safety of BIIB059 in participants = 18 years of age ...Phase
Interventional
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World Trade Center Particulate Matter Induced Cardiorespiratory and Vascular Dysfunction: a MultiOmic Approach
Particulate matter (PM) associated cardiorespiratory and vascular dysfunction (CaRVD) poses a significant global health burden. The World Trade Center (WTC) destruction on September 11, 2001 ...Phase N/A Non-Interventional
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Mechanisms of rAcial dIfferences in the relatioNship between Obstructive Sleep Apnea and in vivo Tau deposition in the context of AmYloid burden
African-Americans (blacks) have two times the risk of developing Alzheimer’s disease (AD) compared to non-Hispanic whites.1-6 Neuropathological studies show blacks with more mixed ...Phase
Non-Interventional
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Intradialytic Myocardial Study Stunning in Maintenance Hemodialysis Patients: A Multi-Center Observational Cohort Study
The purpose of this observational study is to prospectively investigate the frequency and risk factors for intermittent intradialyltic myocardial stunning (IDMS) in maintenance hemodialysis patients ...Phase N/A Non-Interventional
