Displaying 447 (all) recruiting clinical trials.
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Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations
The purpose of this study is to determine if a protein called fibroblast growth factor-2 (FGF-2) can be safely put on the eardrum and help ... -
Patient Expectations Following Flexor Tendon Repair
The purpose of this research study is to examine what patients expect to experience following surgical repair of a flexor tendon injury. Recovery from a ... -
Elucidating Neural Mechanisms and Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder
The purpose of this research study is to understand to how Mindfulness-Based Stress Reduction (MBSR)compared to a Stress Education (SE) class works for patients ... -
An Interventional Multi-Center investigation of Single Level Transforaminal Lumber Interbody Fusion (TLIF) Stabilized with Pedicle Screws
This research study is being conducted to collect data on the safety and effectiveness of a transforaminal lumbar interbody fusion (TLIF) procedure. This is the ... -
A Phase 3 Multi-center Randomized Double-blinded Study of MK-7684 with Pembrolizumab as a Co-formulation (MK-7684A) Versus Pembrolizumab Monotherapy as a First Line Treatment for Participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung Cancer
The purpose of the study is to determine and compare MK-7684A to pembrolizumab alone for participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung ... -
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
The primary objectives of this study are to determine the recommended phase 2 dose(s) (RP2Ds) of JNJ-75276617, as well as the safety and tolerability ... -
Utility of ImmuKnow an Immune Cell Function Assay in a Cardiac Sarcoid Population
The purpose of this study is to assess whether the results of an immune cell function blood test, ImmuKnow can be used to predict responses ... -
A Phase 3 Randomized Multicenter Double-Blind Placebo-Controlled Efficacy and Safety Study of Birtamimab Plus Standard of Care vs. Placebo Plus Standard of Care in Mayo Stage IV Subjects with Light Chain (AL) Amyloidosis
The purpose of the study is to evaluate the efficacy of birtamimab plus standard of care compared to placebo plus standard of care in Mayo ... -
Paradoxical Lucidity in Severe End-Stage Dementia: A Mixed Methods Prospective Study
Many people with severe dementia lose their memory, their ability to communicate with others or care for themselves. Sometimes, though, these people may experience an ... -
A Phase 2 Open-label Multicenter Cohort Study of ALKS 4230 Monotherapy Administered Subcutaneously in Patients With Advanced Cutaneous Melanoma or Intravenously in Patients With Advanced Mucosal Melanoma Who Have Previously Received Anti-PD-[L]1 Therapy - ARTISTRY-6
The purpose of the study is to evaluate the antitumor activity, safety and tolerability of ALKS 4230 given as monotherapy in patients with unresectable and ...