Displaying 553 (all) recruiting clinical trials.
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A Global Randomized Open-label Multicenter Phase 2b/3 Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1)
The main goal of this study is to determine the effectiveness of BJT-778 as a long-term treatment in patients with hepatitis delta virus (HDV) infection.Phase
Interventional
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A Phase 1 Open-Label Multicenter Study of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
To evaluate the safety, tolerability, and DLTs and determine the MTD and/or RDE(s) of INCA33890 in participants with select advanced or metastatic solid ...Phase
Interventional
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A Phase 1 First in Human Randomized Placebo-controlled Trial with a Controlled Gluten Challenge to Evaluate Safety Tolerability Pharmacokinetics and Pharmacodynamics of VTP-1000 in Adults with Celiac Disease
The purpose of this research study is to test a possible new treatment for celiac disease called VTP 1000.Phase
Interventional
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The Impact of Cardiac Rehabilitation on Heart Failure Self-care Maintenance
The purpose of this study is to explore the impact of cardiac rehabilitation (CR) on heart failure self-care maintenance and to identify predictors of CR ...Phase N/A
Non-Interventional
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A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients with Refractory Advanced/Metastatic Microsatellite Stable Colorectal Cancer
This is a Phase 2 study testing whether a combination of TAS-102 and fruquintinib (a selective oral kinase inhibitor) is more effective and safer than ...
Phase
Interventional
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A phase 1 placebo-controlled dose-escalation study of the safety pharmacokinetics and antiviral activity of a potent neutralizing monoclonal antibody in individuals with chronic hepatitis B infection
The purpose of this research study is to evaluate the safety and tolerability of intravenous (through a vein in your arm) infusions of a new ...Phase
Interventional
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Stress and Anxiety Effects on Valuation
The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes.
This study will enroll healthy volunteers ...Phase N/A Interventional
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A Modular Phase I/II Open-label Multicentre Study to Evaluate the Safety PK PD Immunogenicity and Efficacy of AZD4512 Monotherapy or in Combination with other Anticancer agent(s) in subjects with Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
This is a Phase I/II study testing whether the new medicine AZD4512 is safe, effective, and well-tolerated in patients with B-cell Non-Hodgkin Lymphoma (B-NHL ...
Phase
Interventional
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Real world study of efficacy and adherence to subcutaneous vs. intravenous vedolizumab in patients with inflammatory bowel disease using a novel remote MONITORing intervention (MONITOR Study)
The purpose of the study is to assess the effectiveness of a remote monitoring system called Tappt. The study will investigate adherence to medical treatment ...Phase N/A Interventional
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A PHASE 1A/B OPEN-LABEL MASTER STUDY OF PF-07799544 AS A SINGLE-AGENT AND IN COMBINATION WITH OTHER TARGETED AGENTS IN PARTICIPANTS WITH BRAF-MUTANT MELANOMA AND OTHER SOLID TUMORS
This is a first-in-human, open-label, Phase 1a/b master protocol to evaluate safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of PF-07799544 (also ...Phase
Interventional
