Displaying 672 (all) recruiting clinical trials.
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Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation APOLLO Trial
The purpose of the study is to evaluate the safety and efficacy of Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation. Subjects ...Phase N/A
Interventional
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Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD)
IBD Plexus is a research and information exchange platform whose goal is to accelerate research and transform the care of patients with IBD. IBD Plexus ...Phase N/A
Non-Interventional
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The Role of Residual Hearing in Cochlear Implant Outcomes
Cochlear implants (CIs) have the potential to restore high frequency hearing electrically while maintaining residual low frequency hearing, allowing for simultaneous electric and acoustic listening ...Phase N/A Non-Interventional
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VEDOKIDS study: Predicting response to Vedolizumab in Pediatric Inflammatory Bowel Diseases including drug levels: a multi-center prospective Pan- European cohort study (P-ECCO and ESPGHAN)
Vedolizumab (VDZ) is a humanized immunoglobulin G1 monoclonal antibody acting against a4ß7 integrin which modulates lymphocyte trafficking in the gut. Results from the adult GEMINI-1 ...Phase N/A Non-Interventional
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Site for A Multi-Center Prospective Randomized Controlled Trial Comparing the Safety and Effectiveness of prodisc C SK and prodisc C Vivo to Mobi-C Cervical Disc in the Treatment of Two-Level Symptomatic Cervical Disc Disease (SCDD)
Research study to evaluate the safety and effectiveness of prodisc C SK and prodisc C Vivo versus Mobi-C (currently available on market).Phase
Interventional
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Non-invasive biomarkers for neonatal outcomes in preterm infants
Despite modern advances that have greatly improved the health outcomes for preterm infants, the field of neonatology still lacks reliable prognostic tools for many disorders ...Phase N/A Non-Interventional
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Microbial and human biomarkers of thoracic disease after lung transplantation
We will prospectively collect airway and blood samples on 200 subjects undergoing lung transplantation. We will evaluate airway microbial signatures associated with local (lower airway ...Phase N/A Non-Interventional
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Multi-Center Prospective Evaluation of Complex Adult Spinal Deformity Surgery (CADS)
The goal of this study is to evaluate surgical treatment outcomes of complex adult spinal deformity patients, including radiographic and clinical outcomes, surgical and postoperative ...Phase N/A Non-Interventional
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New onset refractory status epilepticus (NORSE)
This is a multi-site study aiming at creating a biorepository of a rare disease, new onset refractory status epilepticus (NORSE), to establish clinical characteristics, outcomes ...Phase N/A Non-Interventional
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TSPO-ligand PET imaging in autoimmune epilepsy
This study will investigate the role of TSPO-PET imaging in autoimmune epilepsy, to quantify and visualize neuroinflammation. This study may support the role for TSPO-PET ...Phase N/A Non-Interventional
