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Mobilis Laboratory Subject Registry
The Mobilis Laboratory Subject Registry is a tool used to recruit healthy individuals and those with stroke for IRB-approved studies. The Registry will include circumscribed ...Phase N/A
Non-Interventional
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A SINGLE-CENTER OBSERVATIONAL LONGITUDINAL STUDY ON THE EFFECT OF SLOW WAVE SLEEP (SWS) CHARACTERISTICS AND RACE AND ETHNICITY ON AMYLOID BURDEN (A MARKER OF ALZHEIMER S DISEASE RISK) AMONG COGNITIVELY NORMAL ELDERLY.
African-Americans (AAs) have an increased prevalence of both Alzheimer’s disease (AD) and vascular risk factors for AD such as diabetes and hypertension when compared ...Phase N/A
Interventional
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THE ROLE OF THE MICROBIOME IN MONOZYGOTIC TWINS WITH PSORIASIS AND PSORIATIC ARTHRITIS
We propose a longitudinal study of monozygotic twins discordant for psoriatic disease. Subjects will be characterized with detailed clinical questionnaires in addition to blood, fecal ...Phase N/A Non-Interventional
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Site for WUH TrialNet: NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
Site for The TrialNet Natural History Study of the Development of T1D is divided into Screening and Monitoring stages. Each stage will require separate informed ...Phase N/A Non-Interventional
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Relationship between the ocular microbiome and pseudoexfoliation syndrome/glaucoma and cataracts
Observational study to determine the microbiome structure of the eye, mouth, and skin of subjects with pseudo exfoliation syndrome, pseudoexfoliation glaucoma, and cataracts before and ...Phase N/A Non-Interventional
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Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation.
The Edwards PASCAL provides a transcatheter treatment for patients suffering from mitral regurgitation.The Edwards PASCAL System was designed to provide physicians a system that ...Phase N/A Interventional
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Rheumatology SAMPLE (Specimen And Matched Phenotype Linked Evaluation) Registry and Biorepository
In this research proposal, we will develop a clinical registry containing information related to the patient’s ethnicity, race, gender, age, medications, specific disease or ...Phase N/A Non-Interventional
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Platelet Activity and Vascular Health in System Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a remarkably complex disease that poses several challenges to the clinician, including heterogeneity of presentation, undulating course, and elevated risk ...Phase N/A Non-Interventional
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AWARE II (AWAreness during REsuscitation) - A Multi-Centre Observational Study of the Relationship between the Quality of Brain Resuscitation and Consciousness Neurological Functional and Cognitive Outcomes following Cardiac Arrest
A multicenter observational study of 1500 hospital occurring cardiac arrests as defined by the cessation of heartbeat and respiration. This study will be carried out ...Phase N/A Non-Interventional
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Neuroenergetic Adaptations in Alzheimer's Disease: Implications on Amyloid Burden and Cognition
Alzheimer’s disease (AD) accounts for the majority of dementia cases worldwide. The number of persons with AD in the US is expected to reach ...Phase N/A Interventional
