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Behavioral Economics Trial To Enhance Regulation of Blood Pressure (BETTER-BP)
The goal of this research study is to understand whether a lottery program implemented for 6 months can improve medication adherence, and consequently, systolic blood ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Phase 2 Study Comparing the Efficacy and Safety of Tirzepatide versus Placebo in Patients with Nonalcoholic Steatohepatitis (NASH)
This study will examen whether the investigational drug, tirzepatide, is safe and able to help study participants with nonalcoholic steatohepatitis (NASH). “Investigational” means that the ...Phase
Interventional
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MULTICENTER PHASE II NEOADJUVANT AND ADJUVANT STUDY OF ALECTINIB ENTRECTINIB OR VEMURAFENIB PLUS COBIMETINIB IN PATIENTS WITH STAGES I-III NON-SMALL CELL LUNG CANCER WITH ALK ROS1 NTRK OR BRAF V600E MOLECULAR ALTERATIONS
The purpose of the trial is to determine the efficacy and safety of drugs in patients with untreated non-small cell lung cancer (NSCLC) tumors. In ...Phase
Interventional
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A Phase 2 Study of BIO 300 in Patients with COVID-19
COVID-19 is caused by a virus that triggers inflammation of the lungs. This inflammation may damage the lungs and lead to scarring. This scarring causes ...Phase
Interventional
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Innovative Trial for Understanding the Impact of Targeted Therapies in NF2 (INTUITT-NF2)
The purpose of the study is to evaluate the biological activity of systemic therapies in people with Neurofibromatosis type 2 (NF2) related tumors. Tumor types ...Phase
Interventional
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ANBL1821: A Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO) (IND# 141913) in Children with Relapsed Refractory or Progressive Neuroblastoma
The purpose of the study is to determine how well irinotecan hydrochloride, temozolomide, and dinutuximab work with or without eflornithine in treating patients with neuroblastoma ...Phase
Interventional
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Alexion NEPH-202 Ravulizumab trial
The purpose of the study is to evaluate the safety and efficacy of the study treatment in participants with Lupus Nephritis (LN).This study involves ...Phase
Interventional
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Cannabidiol for Treating PTSD symptoms and Neurocognitive Impairment in PTSD and PTSD Comorbid with TBI: A Placebo-controlled RCT with Neuralcircuit centered Precision Medicine Prediction of Response
PTSD is a disorder where someone has difficulty recovering after a traumatic event. Symptoms may include nightmares or unwanted memories of the trauma, avoidance of ...Phase
Interventional
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Abaloparatide versus Placebo for Pelvic Fracture Healing - A Phase 2 Randomized Controlled Trial
The purpose of this study is to determine whether Abaloparatide, also known as Tymlos can help to heal a broken bone (fracture) in the pelvis ...Phase
Interventional
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A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of DCR-PHXC in Patients With Primary Hyperoxaluria Type 1 or 2 and Severe Renal Impairment With or Without Dialysis
The purpose of this study is to learn whether the study drug DCR-PHXC is safe and able to treat patients with Primary Hyperoxaluria Type 1 ...Phase
Interventional
