Displaying 17 (all) recruiting clinical trials.
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A Randomized Open-label Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-based Chemotherapy in Patients with EGFR-mutated Non-small Cell Lung Cancer and Disease Progression on EGFR Tyrosine Kinase Inhibitor Therapy
This is Phase 2/3 study testing a new medicine called iza-bren (also known as izalontamab brengitecan or BL-B01D1) for treating advanced lung cancer that ...
Phase
Interventional
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STRIDE II: A Study of Patients with Lower Extremity Acute Limb Ischemia to Remove Thrombus with the Indigo Aspiration System
The purpose of this study is to collect and evaluate clinical evidence supporting the safety and performance of the Indigo Aspiration System in a patient ...Phase
Interventional
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ICONIC-CD Protocol 77242113CRD3001: A Phase 2b/3 Randomized Double-blind Placebo-Controlled Parallel Group Multicenter Protocol to Evaluate the Efficacy and Safety of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
The purpose of this research study is to help researchers understand more about the possible effectiveness and safety of icotrokinra in patients with moderately to ...Phase
Interventional
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A Global Multicenter Randomized Double-Blind Placebo-Controlled Phase 2/3 Study of EIK1001 in Combination with Pembrolizumab and Chemotherapy in Participants with Stage 4 Non-Small Cell Lung Cancer (TeLuRide-008)
This Phase 2/3 study is testing whether adding EIK1001 (investigational drug) to the combination of pembrolizumab and chemotherapy is more effective in treating patients ...
Phase
Interventional
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A Phase 2b/3 Adaptive Randomized Double-blind Placebo-controlled Multicenter Study to Assess the Efficacy and Safety of Danicamtiv in Participants with Symptomatic Genetic and Familial Dilated Cardiomyopathy
Currently, there are no approved drugs that are designed specifically to treat dilated cardiomyopathy (DCM). This study is being done to evaluate how well the ...Phase
Interventional
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An Adaptive 2-Part Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Efficacy and Safety of IKT-001 in Pulmonary Arterial Hypertension
The purpose of this study is to evaluate the effectiveness and safety of IKT-001 compared to placebo for the treatment of pulmonary arterial hypertension (PAH).Phase
Interventional
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Transcatheter Tricuspid Valve Replacement using the Medtronic Intrepid TTVR System in patients with Severe Symptomatic Tricuspid Regurgitation (PATHFINDER)
This study tests whether the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) system is safe and works well for people with a badly leaking tricuspid ...Phase
Interventional
