Displaying 513 (all) recruiting clinical trials.
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EARLY DETECTION OF ALPHA-SYNUCLEIN DISEASE Single-center cross-sectional and longitudinal non-interventional observational study of biomarkers in prodromal synucleinopathy
Single-center, cross-sectional and longitudinal exploratory observational study of approximately 80 patients with diagnoses of pure autonomic failure (PAF), Parkinson´s Disease, Multiple System Atrophy, Lewy ...Phase N/A
Non-Interventional
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Elucidating Neural Mechanisms and Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder
Mindfulness-Based Stress Reduction (MBSR) has demonstrated efficacy for Generalized Anxiety Disorder (GAD), yet there remains a major knowledge gap about its neural mechanisms. Neuroimaging studies ...Phase N/A
Interventional
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Site for AN INTERVENTIONAL MULTI-CENTER INVESTIGATION OF SINGLE LEVEL TRANSFORAMINAL LUMBAR INTERBODY FUSION (TLIF) STABILIZED WITH PEDICLE SCREWS
Site for An interventional, multi-center (up to 15), prospective, non-blinded investigation of single-level TLIF stabilized with pedicle screws. The purpose is to intend to treat ...Phase N/A Interventional
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A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute LeukemiaPhase
Interventional
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A Multi-Center Observational Study Assessing the Utility of an Immune Cell Function Assay in a Cardiac Sarcoid Population
Sarcoid is an autoimmune disease that can be found in any and every organ system. The greatest degree of morbidity and mortality comes from cardiac ...Phase N/A Non-Interventional
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Paradoxical Lucidity in Severe End-Stage Dementia: A Mixed Methods Prospective Study
Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal ...Phase N/A Non-Interventional
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The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis (SAVVE) Study Trial
To assess the safety and effectiveness of the Hancock Jaffe VenoValve for the treatment of patients with deep venous valvular insufficiency A prospective, non-blinded, single-arm ...Phase
Interventional
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A randomized phase II trial of adjuvant trastuzumab emtansine (T-DM1) followed by subcutaneous trastuzumab versus paclitaxel in combination with subcutaneous trastuzumab for Stage I HER2-positive breast cancer (ATEMPT 2.0)
This is a randomized phase II adjuvant study for women and men with Stage I HER2-positive invasive breast cancer. At least 500 eligible patients will ...Phase
Interventional
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Psoriatic Arthritis Research Consortium (PARC - R01)
Physician assessments do not fully capture the patient’s experience of the disease. As in many other conditions, patient input in assessing disease status and ...Phase N/A Non-Interventional
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NYU Langone Post-COVID Registry
This is an observational registry study with medical record review to assess characteristics, management, and outcomes of patients who received a diagnosis of COVID-19. We ...Phase N/A Non-Interventional
