Displaying 555 (all) recruiting clinical trials.
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Combined Craniomaxillofacial and Upper Extremity Allotransplantation
The purpose of this study is to evaluate functional and aesthetic outcomes of combined facial and upper extremity composite tissue allografts on patients who have ...Phase N/A
Interventional
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Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation APOLLO Trial
The purpose of the study is to evaluate the safety and efficacy of Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation. Subjects ...Phase N/A Interventional
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Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD)
IBD Plexus is a research and information exchange platform whose goal is to accelerate research and transform the care of patients with IBD. IBD Plexus ...Phase N/A
Non-Interventional
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Site for A Multi-Center Prospective Randomized Controlled Trial Comparing the Safety and Effectiveness of prodisc C SK and prodisc C Vivo to Mobi-C Cervical Disc in the Treatment of Two-Level Symptomatic Cervical Disc Disease (SCDD)
Research study to evaluate the safety and effectiveness of prodisc C SK and prodisc C Vivo versus Mobi-C (currently available on market).Phase
Interventional
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Non-invasive biomarkers for neonatal outcomes in preterm infants
Despite modern advances that have greatly improved the health outcomes for preterm infants, the field of neonatology still lacks reliable prognostic tools for many disorders ...Phase N/A Non-Interventional
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Microbial and human biomarkers of thoracic disease after lung transplantation
We will prospectively collect airway and blood samples on 200 subjects undergoing lung transplantation. We will evaluate airway microbial signatures associated with local (lower airway ...Phase N/A Non-Interventional
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Multi-Center Prospective Evaluation of Complex Adult Spinal Deformity Surgery (CADS)
The goal of this study is to evaluate surgical treatment outcomes of complex adult spinal deformity patients, including radiographic and clinical outcomes, surgical and postoperative ...Phase N/A Non-Interventional
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New onset refractory status epilepticus (NORSE)
This is a multi-site study aiming at creating a biorepository of a rare disease, new onset refractory status epilepticus (NORSE), to establish clinical characteristics, outcomes ...Phase N/A Non-Interventional
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WUH: COG# AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
?Despite recent improvements in outcome for children with newly diagnosed high-risk neuroblastoma, cure rates remain unsatisfactory. Further, these gains have been the result of interventions ...Phase
Interventional
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WUH: "ANBL1531: A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL) (IND# 134379)"
?Despite recent improvements in outcome for children with newly diagnosed high-risk neuroblastoma, cure rates remain unsatisfactory. Further, these gains have been the result of interventions ...Phase
Interventional
