Displaying 557 (all) recruiting clinical trials.
-
A Randomized single-blind placebo-controlled study on the effect of perioperative administration of ketamine on pain after surgery for orthopedic trauma: A Pilot Trial
The purpose of this study is to examine whether ketamine given during and after surgery (in the recovery room) can improve postoperative pain, mood, and ...Phase
Non-Interventional
-
A double blind randomised placebo-controlled trial evaluating the efficacy and safety of nerandomilast over 26 weeks in patients with Systemic Autoimmune Rheumatic Diseases associated Interstitial Lung Diseases (SARD-ILD)
The purpose of this research study is to test a new drug called nerandomilast in participants with Systemic Auto-immune Rheumatic Diseases associated Interstitial Lung Diseases ...Phase
Interventional
-
In vivo assessment of the mitochondrial complex I in subjects with schizophrenia
The goal of the study is to use novel brain imaging techniques to measure some part of how the brain uses energy. The study will ...Phase N/A Interventional
-
A Phase II 26-week double-blind placebo-controlled study to assess the safety tolerability pharmacokinetics and efficacy of ONO-2020 in patients with mild to moderate Alzheimer s Disease
This study will evaluate the safety and effectiveness of the drug ONO-2020 for mild to moderate Alzheimer's disease. The study will specifically investigate how ...Phase
Non-Interventional
-
A Phase II Study of DRP-104 a glutamine antagonist in patients with NFE2L2/KEAP1-altered Non-Small Cell Lung Cancer and Gastroesophageal Cancer
This is a Phase 2 study testing a new medicine called DRP-104 (a glutamine antagonist) in patients with non-small cell lung cancer (NSCLC). These patients ...
Phase
Interventional
-
A Phase I Clinical Study to Evaluate the Safety Tolerability Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Subjects with Advanced Solid Tumors
This is a Phase 1 study testing the study medicine GSK5733584 (B7-H4 targeted antibody-drug conjugate (ADC )) in patients with advanced solid tumors. The study drug ...
Phase
Interventional
-
IMVT-1402-2801 - A Phase 2b Multicenter Randomized Double-Blind Placebo-Controlled Parallel-Group Study to Assess the Efficacy Safety and Tolerability of IMVT-1402 in Adult Participants with Primary Sjogren s Disease with Moderate to Severe Systemic Disease Activity
The purpose of this study is to see if IMVT-1402 is safe and helps people with Sjogren’s Disease (SjD) with moderate-to-severe disease activity.Phase
Interventional
-
Interventional randomized double-blind placebo-controlled optional open-label extension trial of Lu AF82422 in participants with Multiple System Atrophy.
The purpose of this trial is to investigate whether Lu AF82422 is safe and effective in treating patients with multiple system atrophy (MSA). This trial ...Phase
Interventional
-
A Phase III Randomised Double-blind Placebo-controlled Event-driven Study to Assess the Efficacy Safety and Tolerability of Baxdrostat in Combination with Dapagliflozin Compared with Dapagliflozin Alone on Renal Outcomes and Cardiovascular Mortality in Participants with Chronic Kidney Disease and High Blood Pressure
The purpose of this study is to investigate the efficacy, safety and tolerability of baxdrostat in combination with dapagliflozin, compared with placebo and dapagliflozin intreating ...Phase
Interventional
-
EXpanding Prenatal cell free DNA screening Across moNogenic Disorders (EXPAND)
The purpose of this study is to develop an investigational non-invasive prenatal genetic screening test that will assess a baby’s risk of being affected ...Phase N/A Non-Interventional
