Displaying 603 (all) recruiting clinical trials.
-
DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs
This study employs a placebo-controlled randomized cross-over design to investigate the impact of body weight and aspirin dose on levels of specialized pro-resolving lipid mediators ...Phase
Interventional
-
A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02D
The Master Protocol is a Phase 1/2, rolling arm, multicenter, open-label, adaptive design study that will evaluate within this substudy protocol the efficacy of ...Phase
Interventional
-
A Single-Center Observational Study to Develop EEG Biomarkers of Transition from Acute to Chronic Pain
We will enroll acute and chronic low back pain and control subjects. We will record high density EEG in these subjects, along with pain and ...Phase N/A
Non-Interventional
-
Reverse End to Side Transfer for Severe Cubital Tunnel Syndrome
This prospective study will investigate outcomes in patients with severe cubital tunnel syndrome between patients that undergo reverse end to side (RETS) transfer and patients ...Phase N/A Non-Interventional
-
Mesoscopic Biomarkers of Neurodegeneration and Inflammation with Diffusion MRI
In this study, novel diffusion MRI markers in brain white matter will be evaluated to yield clinically feasible non-invasive MR markers that are sensitive and ...Phase N/A Non-Interventional
-
The PROP-RD Study: A Prospective Registry for the Study of Outcomes and Predictors in Pouchitis and Pouch-Related Disorders
Purpose: Create a prospective registry of patients with pouch-related conditions to allow for longitudinal assessment of outcomes. Participants: 320 patients from 8 centers who are ...Phase N/A Non-Interventional
-
Site for Studies of Patients with Implanted Intracranial Electrodes
Site for The overall goals of this research protocol are 1) to better understand the function of cortical sites that are measured with scalp electrodes ...Phase N/A Non-Interventional
-
Personalized Dietary Management in Type 2 Diabetes Lay title: The DIAbetes TELEmedicine MEDiterranean Diet Study (DIATELEMED)
Limiting blood sugar peaks following meals is an important treatment goal in the management of type 2 diabetes, but evidence is mixed regarding the best ...Phase
Interventional
-
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1 BRCA2 or PALB2 Mutation
This phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic cancer that ...Phase
Interventional
-
A SINGLE-CENTER OBSERVATIONAL STUDY OF THE IMPACT OF TREMOR AFFECTING THE VOICE ON DEGLUTITION
Tremor affects ~1% of the global population or nearly 80 million people. In spite of this staggering figure, both nomenclature and treatment approaches are inconsistent ...Phase N/A Non-Interventional
