Displaying 649 (all) recruiting clinical trials.
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A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
The primary objectives of this study are to determine the recommended phase 2 dose(s) (RP2Ds) of JNJ-75276617, as well as the safety and tolerability ... -
Organized sports participation among patients who have undergone Ponseti treatment for Idiopathic Clubfoot
The purpose of this study is to evaluate the regularity of sports participation in children, with a diagnosis of clubfoot, at the grade school, middle ... -
Utility of ImmuKnow an Immune Cell Function Assay in a Cardiac Sarcoid Population
The purpose of this study is to assess whether the results of an immune cell function blood test, ImmuKnow can be used to predict responses ... -
A Phase 3 Randomized Multicenter Double-Blind Placebo-Controlled Efficacy and Safety Study of Birtamimab Plus Standard of Care vs. Placebo Plus Standard of Care in Mayo Stage IV Subjects with Light Chain (AL) Amyloidosis
The purpose of the study is to evaluate the efficacy of birtamimab plus standard of care compared to placebo plus standard of care in Mayo ... -
Paradoxical Lucidity in Severe End-Stage Dementia: A Mixed Methods Prospective Study
Many people with severe dementia lose their memory, their ability to communicate with others or care for themselves. Sometimes, though, these people may experience an ... -
A Randomized Comparative Effectiveness Study of Staged Complete Revascularization with Percutaneous Coronary Intervention to Treat Coronary Artery Disease vs Medical Management Alone in Patients with Symptomatic Aortic Valve Stenosis undergoing Elective
The purpose of this study is to find out, in patients with coronary artery disease (CAD) who had successful transcatheter aortic valve replacement (TAVR) with ... -
Depression treatment and A dynamics: A study of Alzheimer s disease risk
The purpose of this research study is to test if a reduction in depressive symptoms in response to treatment with an antidepressant improves levels of ... -
Lung and Diaphragm Ultrasound in Dyspneic Patients
Shortness of breath is one of the most common symptoms experienced by patients with lung conditions. Patients with shortness of breath frequently undergo many tests ... -
A Phase 2 Open-label Multicenter Cohort Study of ALKS 4230 Monotherapy Administered Subcutaneously in Patients With Advanced Cutaneous Melanoma or Intravenously in Patients With Advanced Mucosal Melanoma Who Have Previously Received Anti-PD-[L]1 Therapy - ARTISTRY-6
The purpose of the study is to evaluate the antitumor activity, safety and tolerability of ALKS 4230 given as monotherapy in patients with unresectable and ... -
MASALA Study Expansion
The purpose of this research study is to understand the causes of heart disease and stroke in South Asians and compare these causes to those ...