Displaying 628 (all) recruiting clinical trials.
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Elucidating Neural Mechanisms and Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder
The purpose of this research study is to understand to how Mindfulness-Based Stress Reduction (MBSR)compared to a Stress Education (SE) class works for patients ... -
An Interventional Multi-Center investigation of Single Level Transforaminal Lumber Interbody Fusion (TLIF) Stabilized with Pedicle Screws
This research study is being conducted to collect data on the safety and effectiveness of a transforaminal lumbar interbody fusion (TLIF) procedure. This is the ... -
A Phase 3 Multi-center Randomized Double-blinded Study of MK-7684 with Pembrolizumab as a Co-formulation (MK-7684A) Versus Pembrolizumab Monotherapy as a First Line Treatment for Participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung Cancer
The purpose of the study is to determine and compare MK-7684A to pembrolizumab alone for participants with PD-L1 Positive (TPS>=1%) Metastatic Non-Small Cell Lung ... -
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
The primary objectives of this study are to determine the recommended phase 2 dose(s) (RP2Ds) of JNJ-75276617, as well as the safety and tolerability ... -
Organized sports participation among patients who have undergone Ponseti treatment for Idiopathic Clubfoot
The purpose of this study is to evaluate the regularity of sports participation in children, with a diagnosis of clubfoot, at the grade school, middle ... -
Utility of ImmuKnow an Immune Cell Function Assay in a Cardiac Sarcoid Population
The purpose of this study is to assess whether the results of an immune cell function blood test, ImmuKnow can be used to predict responses ... -
A Phase 3 Randomized Multicenter Double-Blind Placebo-Controlled Efficacy and Safety Study of Birtamimab Plus Standard of Care vs. Placebo Plus Standard of Care in Mayo Stage IV Subjects with Light Chain (AL) Amyloidosis
The purpose of the study is to evaluate the efficacy of birtamimab plus standard of care compared to placebo plus standard of care in Mayo ... -
Paradoxical Lucidity in Severe End-Stage Dementia: A Mixed Methods Prospective Study
Many people with severe dementia lose their memory, their ability to communicate with others or care for themselves. Sometimes, though, these people may experience an ... -
A Randomized Comparative Effectiveness Study of Staged Complete Revascularization with Percutaneous Coronary Intervention to Treat Coronary Artery Disease vs Medical Management Alone in Patients with Symptomatic Aortic Valve Stenosis undergoing Elective
The purpose of this study is to find out, in patients with coronary artery disease (CAD) who had successful transcatheter aortic valve replacement (TAVR) with ... -
Depression treatment and A dynamics: A study of Alzheimer s disease risk
The purpose of this research study is to test if a reduction in depressive symptoms in response to treatment with an antidepressant improves levels of ...