Displaying 698 (all) recruiting clinical trials.
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THE PROSPECTIVE NATURAL HISTORY OF FAMILIAL DYSAUTONOMIA
Our ultimate goal is to develop new treatments for patients with familial dysautonomia (FD, OMIM 223900). We also want to learn which specific nerve populations ...Phase N/A
Non-Interventional
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MICROBiome Involvement in Outcomes of Methotrexate Efficacy-RA
This is a prospective, observational, proof-of-principle, open-label, single-blinded study looking at the effects of the gut microbiome on the metabolism and response to methotrexate treatment ...Phase N/A Non-Interventional
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Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTIONInternational Clinical Database and Repository
Antiphospholipid syndrome (APS) is a disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss. APS can occur as a primary ...Phase N/A Non-Interventional
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OUTCOMES AFTER REPAIR OF CHRONIC PECTORALIS MAJOR RUPTURE WITH ACHILLES TENDON ALLOGRAFT
We are studying outcomes and comparing strength between the affected and unaffected arm in patients who have undergone surgical repair or reconstruction of a chronic ...Phase N/A Non-Interventional
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Gaucher Disease Outcome Survey (GOS)
The Gaucher Outcome Survey (GOS) is a long term observational survey. This survey aims to collect as much information as possible from as many Gaucher ...Phase N/A Non-Interventional
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Risk factors for sudden unexplained death in epilepsy (SUDEP)
The registry is a database created to document SUDEP (sudden unexplained death in epilepsy patients) cases. Our goals are to increase knowledge and awareness about ...Phase
Non-Interventional
Accepts Healthy Volunteer
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ANBL1531: A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL) (IND# 134379)
Despite recent improvements in outcome for children with newly diagnosed high-risk neuroblastoma, cure rates remain unsatisfactory. Further, these gains have been the result of interventions ...Phase
Interventional
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Anomalous Aortic Origin of a Coronary Artery (AAOCA): Establishing a Multi-Institutional Registry
This is a retrospective and longitudinal cohort study. Subjects will be enrolled either when identified from medical records or when diagnosed with AAOCA. Baseline demographics ...Phase N/A Non-Interventional
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Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
The proposed study is a double-blind, 2-group randomized controlled trial designed to contrast acute and persisting effects of topiramate to those of placebo treatment in ...Phase
Interventional
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Site for WUH APOLLO TRIAL: Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation APOLLO Trial
Site for Multi-center, global, prospective, randomized, interventional, pre-market trial Subjects will be randomized on 1:1 basis to either TMVR with the Medtronic Intrepid™ TMVR ...Phase N/A Interventional
