Displaying 595 (all) recruiting clinical trials.
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A SINGLE-CENTER OBSERVATIONAL LONGITUDINAL STUDY ON THE EFFECT OF SLOW WAVE SLEEP (SWS) CHARACTERISTICS AND RACE AND ETHNICITY ON AMYLOID BURDEN (A MARKER OF ALZHEIMER S DISEASE RISK) AMONG COGNITIVELY NORMAL ELDERLY.
African-Americans (AAs) have an increased prevalence of both Alzheimer’s disease (AD) and vascular risk factors for AD such as diabetes and hypertension when compared ...Phase N/A
Interventional
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Anti-Viral Therapy in Alzheimer's Disease
This study is being conducted to evaluate if the generic anti-viral medication, valacyclovir, is helpful in treating Alzheimer’s disease in patients who have tested ...Phase
Interventional
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THE ROLE OF THE MICROBIOME IN MONOZYGOTIC TWINS WITH PSORIASIS AND PSORIATIC ARTHRITIS
We propose a longitudinal study of monozygotic twins discordant for psoriatic disease. Subjects will be characterized with detailed clinical questionnaires in addition to blood, fecal ...Phase N/A
Non-Interventional
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Site for WUH TrialNet: NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
Site for The TrialNet Natural History Study of the Development of T1D is divided into Screening and Monitoring stages. Each stage will require separate informed ...Phase N/A Non-Interventional
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Relationship between the ocular microbiome and pseudoexfoliation syndrome/glaucoma and cataracts
Observational study to determine the microbiome structure of the eye, mouth, and skin of subjects with pseudo exfoliation syndrome, pseudoexfoliation glaucoma, and cataracts before and ...Phase N/A Non-Interventional
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Transcranial Direct Current Stimulation (tDCS) for the Management of Multiple Sclerosis Related Fatigue
This is a pragmatic clinical trial that aims to determine the effect of tDCS on symptomatic fatigue and can directly inform care providers. Our innovative ...Phase
Interventional
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Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation.
The Edwards PASCAL provides a transcatheter treatment for patients suffering from mitral regurgitation.The Edwards PASCAL System was designed to provide physicians a system that ...Phase N/A Interventional
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Rheumatology SAMPLE (Specimen And Matched Phenotype Linked Evaluation) Registry and Biorepository
In this research proposal, we will develop a clinical registry containing information related to the patient’s ethnicity, race, gender, age, medications, specific disease or ...Phase N/A Non-Interventional
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Platelet Activity and Vascular Health in System Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a remarkably complex disease that poses several challenges to the clinician, including heterogeneity of presentation, undulating course, and elevated risk ...Phase N/A Non-Interventional
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AWARE II (AWAreness during REsuscitation) - A Multi-Centre Observational Study of the Relationship between the Quality of Brain Resuscitation and Consciousness Neurological Functional and Cognitive Outcomes following Cardiac Arrest
A multicenter observational study of 1500 hospital occurring cardiac arrests as defined by the cessation of heartbeat and respiration. This study will be carried out ...Phase N/A Non-Interventional
