Displaying 649 (all) recruiting clinical trials.
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A Phase 3 Multicenter Randomized Open-Label Trial of Epcoritamab in Combination with R-CHOP compared to R-CHOP in Subjects with High-Risk Diffuse Large B-Cell Lymphoma
This is a study to see if a new medicine called epcoritamab (works by binding to CD3 and CD20 on cells, which brings T cells ...
Phase
Interventional
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Phase 1 First-in-Human Dose Escalation and Expansion Study to Assess Safety and Tolerability of Intravenous Administration of ICVB-1042 in Patients with Advanced Solid Tumors
This study is about a new medicine called ICVB-1042 (kills tumor cells) for people with advanced solid tumors. It has two parts: one where we ...
Phase
Interventional
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A Phase II multicenter open-label single-arm dose escalation study of Asciminib monotherapy in 2nd and 1st Line Chronic Phase Chronic Myelogenous Leukemia (ASC2ESCALATE)
This study involves two groups of people with a type of blood cancer called chronic myeloid leukemia in its early stage. In one group, there ...
Phase
Interventional
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A phase I open-label multi-center study of KFA115 as a single agent and in combination with tislelizumab in patients with select advanced cancers
This study is testing a new medicine called KFA115 (FDA approved) for patients with advanced or widespread cancers. It has two main parts: one where ...
Phase
Interventional
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Safety and Effectiveness Evaluation of the THERMOCOOL SMARTTOUCH SF Catheter with the TRUPULSE Generator for treatment of drug refractory symptomatic Paroxysmal Atrial Fibrillation (PAF)
This is a prospective, single arm, multi-center, clinical evaluation of the PF/RF ablation system (THERMOCOOL SMARTTOUCH™ SF (STSF) Catheter and TRUPULSE™ Generator) to demonstrate ...Phase N/A Interventional
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Young Onset Parkinson's disease Subtypes and Pathogenic Mechanisms (YOPD Study)
Young Onset Parkinson's disease (YOPD) occurs in patients before the age of 50 years. Our current knowledge about the mechanisms that cause YOPD is ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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A Randomised Double-blind Placebo-controlled Multicentre Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With Non-cirrhotic Non-alcoholic Steatohepatitis (NASH) and Fibrosis Stages F2 and F3
This Phase 3 study is conducted to evaluate Lanifibranorin adults with NASH and liver fibrosis stage 2 or 3 and consists of 2 parts: Part ...Phase
Interventional
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The HistoSonics Edison System for treatment of primary solid renal tumors using histotripsy (#HOPE4KIDNEY US)
This study is testing the HistoSonics Edison System for treating kidney tumors using histotripsy (involves using focused ultrasound beams from outside the body to create ...
Phase
Interventional
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Quantification of Multi-Compartment T1 Relaxation and Magnetization Transfer in Biological Tissue: From Biophysics to Biomarkers for Multiple Sclerosis
The purpose of this study is to evaluate the efficacy of multi-compartment T1 relaxation and magnetization transfer for detecting subtle changes in normal-appearing brain tissue ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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A Multicenter Randomized Double-blind Placebo-controlled Phase 3 Study Evaluating the Efficacy and Safety of Subcutaneous Anifrolumab in Adult Subjects with Active Systemic Lupus Erythematosus
The purpose of this study is evaluating the efficacy and safety of SC antifrolumab in adult patients with moderate -to-severe SLE despite receiving standard therapy ...Phase
Interventional
