Displaying 668 (all) recruiting clinical trials.
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Elacestrant versus Standard Endocrine Therapy in Women and Men with Node-positive Estrogen Receptor-positive HER2-negative Early Breast Cancer with High Risk of Recurrence A Global Multicenter Randomized Open-label Phase 3 Study (ELEGANT)
This is a phase 3 study, comparing the new medicine called Elacestrant (selective estrogen receptor degrader) with standard hormonal treatments in patients with ER-positive/HER2-negative ...
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mHealth-CArdiac REhabilitation for INOCA (INOCA-CARE)
This study will enroll participants with the condition condition called Ischemia with No-Obstructive Coronary Arteries (INOCA), which means the participant ... -
A Phase II Single-Arm Study of Craniospinal Irradiation with Linac Based Volumetric Modulated Arc Therapy (VMAT) for Patients with Leptomeningeal Metastasis
This study is a non-randomized phase II single-institution trial in which patients who consent to the trial will be treated with linac based VMAT CSI ... -
A Multi-centered Double-blind Randomized Placebo-controlled Parallel Group Phase 2 Study of TEV-56286 for the Treatment of Patients with Multiple System Atrophy
The study is evaluating the safety and effectiveness of "TEV-56286" to treat multiple system atrophy (MSA).
The total duration of participation is just over one ... -
AAML1831: A Phase 3 Randomized Trial for Patients with de novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3
This phase III trial compares standard chemotherapy to therapy with CPX-351 and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without ... -
A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics Pharmacokinetics Safety and Tolerability of REGN7544 an NPR1 Antagonist Monoclonal Antibody in Patients with Postural Orthostatic Tachycardia Syndrome
The purpose of this research study is to research an experimental drug called REGN7544. The study is focused on participants with postural orthostatic tachycardia syndrome ... -
A Prospective Randomized Study of a Novel EEG Neurofeedback System for the Treatment of PTSD Using Machine Learning-Based Amygdala Biomarkers
The main purpose of this study is to confirm Prism training can help U.S. Veterans and civilians with post-traumatic stress disorder (PTSD). We will ... -
EXPANDED ACCESS PROTOCOL (EAP) FOR SUBJECTS RECEIVING IDECABTAGENE VICLEUCEL THAT IS NONCONFORMING FOR COMMERCIAL RELEASE
This study is an expanded access protocol (EAP), meaning it is testing how effective and safe it would be to use medicine called nonconforming Idecabtagene ...
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A Comparison of NeuroSpan Bridge NeuraGen Nerve Guide and Nerve Autograft for Peripheral Nerve Repair (NeuroSpan-1)
The purpose of this research study is to compare three treatments for nerve injuries in the arms or legs: the NeuroSpan Bridge, the NeuraGen Nerve ... -
A single-center observational study of whole and regional brain volumes in patients with pediatric-onset demyelinating diseases
The purpose of this research study is to better understand how the brains of children and young adults with demyelinating diseases, such as multiple sclerosis ...