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Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease
The purpose of this study is to learn more about whether nebulized hypertonic saline can help improve symptoms and clearance of mycobacteria. Hypertonic saline (7 ...Phase N/A
Interventional
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Assessment of immunological and vascular dysfunction in neuropsychiatric post-acute sequelae of SARS-CoV-2 using TSPO PET and MRI
The overarching goal of this study is to develop PET/MR techniques for the diagnosis of neuropsychiatric post-acute sequelae (PASC) of SARS-CoV-2. Our central hypothesis ...Phase N/A
Non-Interventional
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SMall Annuli Randomized To Evolut or SAPIEN Trial (SMART Trial)
The purpose of this trial is to generate clinical evidence on valve safety and performance of self-expanding versus balloon-expandable transcatheter aortic valve replacement in subjects ...Phase N/A Interventional
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Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
This is a cross-sectional study in 100 older adults (n = 100, 50 female, 60–80 years) who are cognitively normal (n = 70) or have mild ...Phase N/A Interventional
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Proactive infliximab optimization using a pharmacokinetic dashboard versus standard of care in patients with Crohn s disease: The OPTIMIZE Trial
This is a randomized, controlled, multicenter, open-label study. All eligible subjects will be randomly assigned in a 1:1 ratio to receive either IFX monotherapy ...Phase N/A Interventional
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A pilot neuroimaging study of adults with prolonged grief disorder (PGD) compared to bereaved controls after death of a spouse or parent
For this study we will recruit an estimated 20 participants to have 10 participants be eligible and complete the study. They will be adults age ...Phase N/A Non-Interventional
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Racial diffErences in the aSsociation Of sLow waVe slEep aNd Tau (RESOLVENT II)
This pilot proposal will examine whether racial differences exist in the association between SWS/SWA and in-vivo regional tau-PET signal for a given level of ...Phase N/A Non-Interventional
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NYU MANAGING EPILEPSY WELL (MEW) STUDY: A RANDOMIZED CONTROLLED TRIAL OF TELEPHONE-BASED SUPPORT FOR PEOPLE WITH EPILEPSY
This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking ...Phase N/A Interventional
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Brain Effects of Lifetime Racial/Ethnic Discrimination on the LC-NE Function and the Risk for Alzheimer's Disease
The current biomarker classification system (i.e., the ATN model) may not fully account for racial disparity and can’t explain the increased prevalence in ...Phase N/A Non-Interventional
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Movement Disorder Genomic Study
With the present study we aim to perform integrated genomic analysis and study on subject-specific cellular models in order to identify genetic causes of rare ...Phase N/A Non-Interventional
