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C-TRACT Study; Chronic Venous Thrombosis; Relief with adjunctive catheter directed therapy
To determine if endovascular therapy (balloon angioplasty and stent placement) should be routinely used to treat disabling iliac vein-obstructive post-thrombotic syndrome, this multicenter randomized clinical ...Phase
Interventional
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A Randomized Trial comparing the Drug-Eluting Stent (DES) Below-the-Knee (BTK) Vascular Stent System (DES BTK Vascular Stent System) vs Percutaneous Transluminal Angioplasty (PTA) Treating Infrapopliteal Lesions in Subjects With Critical Limb Ischemia.
The purpose of this two phased, prospective clinical trial is to demonstrate superior patency rate and acceptable safety in below the knee arteries with lesions ...Phase
Interventional
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Zenith p-Branch Pivotal Study
The purpose of this study is to assess the safety of the Zenith® p-Branch® and how well it works in combination with Atrium iCAST™ covered ...Phase
Interventional
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A phase III randomized double blind parallel group placebo controlled international multicentre study to assess efficacy and safety of Cx601 adult allogeneic expanded adipose-derived stem cells (eASC) for the treatment of complex perianal fistula(
The purpose of this study is to confirm (1) how well the investigational drug, Cx601, works at a single dose of 120 million cells compared ...Phase
Interventional
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Sleep for Stroke Management And Recovery Trial (Sleep SMART)
This research is being done to figure out whether treatment for sleep apnea, in people who have had a stroke or TIA, improves recovery from ...Phase
Interventional
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A Phase 3 Multicenter Open-Label Extension Trial of Oral RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis
The purpose of this study is to see whether ozanimod (RPC1063), (also referred to as the ‘study drug’), is safe and how well it works ...Phase
Interventional
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RESILIENT: REhabilitation at home uSIng mobiLe health In oldEr adults after hospitalizatioN for ischemic hearT disease
The goal of this research study is to understand whether a personalized care plan for home exercise, coupled with the use of mobile health technology ...Phase
Interventional
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A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for Treatment of Antibody-Mediated Rejection in Kidney Transplant Recipients
The purpose of this research study is to investigate the effectiveness and safety of treatment with clazakizumab compared to a placebo (inactive substance) in kidney ...Phase
Interventional
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AALL1631: International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ ALL Testing Imatinib in Combination with Two Different Cytotoxic Chemotherapy Backbones
The goal of this trial is to reduce treatmentrelated morbidity and mortality without adversely impacting disease free survival (DFS) in Standard Risk (SR) patients, who ...Phase
Interventional
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A Phase 3 Study of I-Metaiodobenzylguanidine or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL) (IND# 134379)
?The primary purpose of the study is to assess the effectiveness and safety of targeted radiopharmaceutical therapy with 131I-MIBG or crizotinib for patients with high-risk ...Phase
Interventional
