Displaying 22 (all) recruiting clinical trials.
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Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS = 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)
A randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS = 1 Advanced Gastric and Esophageal ...Phase
Interventional
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TechnoPhage S.A./ A Phase 2b Clinical Study to Evaluate the Safety and Efficacy of Topical Administration of Bacteriophage Therapy TP-102 in Patients with Diabetic Foot Infection.
This research study is a Phase 2b clinical study, which intends to evaluate the safety and the efficacy (how well something works) of the investigational ...Phase
Interventional
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GLP-1 Agonist Treatment for Opioid Use Disorder - A Multi-Site Randomized Placebo-Controlled Trial
The purpose of this research study is to determine whether once-weekly treatment with an investigational drug, semaglutide, may help reduce illicit opioid use compared to ...Phase
Interventional
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A Phase 2a Multicenter Randomized Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Moderate to Severe Crohn's Disease
The purpose of this study is to evaluate the safety and efficacy of using multiple investigational medicines compared to a single medicine in subjects with ...Phase
Interventional
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A Global Randomized Open-label Multicenter Phase 2b/3 Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1)
The main goal of this study is to determine the effectiveness of BJT-778 as a long-term treatment in patients with hepatitis delta virus (HDV) infection.Phase
Interventional
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A Phase 2/3 Efficacy and Safety Study of KPL-387 Treatment in Participants with Recurrent Pericarditis
The purpose of this research study is to learn if KPL-387 is an effective and safe treatment for recurrent pericarditis. The study drug will be ...Phase
Interventional
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An Adaptive Phase 2/3 Multicenter Double-Blind Placebo-Controlled Randomized Parallel 3 Arm Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient s Calcific Aortic Valve Disease with Mild to Moderate Aortic Stenosis (EVOID-AS)
The primary objective of this study is to evaluate the efficacy of DA-1229 vs. placebo in reducing progression of aortic valve calcification in subjects with ...Phase
Interventional
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A Randomized Open-label Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-based Chemotherapy in Patients with EGFR-mutated Non-small Cell Lung Cancer and Disease Progression on EGFR Tyrosine Kinase Inhibitor Therapy
This is Phase 2/3 study testing a new medicine called iza-bren (also known as izalontamab brengitecan or BL-B01D1) for treating advanced lung cancer that ...
Phase
Interventional
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STRIDE II: A Study of Patients with Lower Extremity Acute Limb Ischemia to Remove Thrombus with the Indigo Aspiration System
The purpose of this study is to collect and evaluate clinical evidence supporting the safety and performance of the Indigo Aspiration System in a patient ...Phase
Interventional
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ICONIC-CD Protocol 77242113CRD3001: A Phase 2b/3 Randomized Double-blind Placebo-Controlled Parallel Group Multicenter Protocol to Evaluate the Efficacy and Safety of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
The purpose of this research study is to help researchers understand more about the possible effectiveness and safety of icotrokinra in patients with moderately to ...Phase
Interventional
