Displaying 29 (all) recruiting clinical trials.
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A Phase 3 Randomized Open-label Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment With or Without Bevacizumab Versus Standard of Care After Second-line Platinum-based Doublet Chemotherapy in Participants With Platinum-sensitive Recurrent Ovarian Cancer (TroFuse-022/ENGOT-ov84/GOG-3103)
This is a Phase 3 randomized (split into groups by chance) study designed to compare how well and how safely sacituzumab tirumotecan, with or without ...
Phase
Interventional
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A Phase 3 Randomized Open-label Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab With or Without Bevacizumab Compared With Standard of Care as Firstline Maintenance Treatment for Participants With Persistent Recurrent or Newly Diagnosed Metastatic Cervical Cancer With PD-L1 CPS Greater Than or Equal to 1
This is a Phase 3 study testing a new experimental drug called sacituzumab tirumotecan (sac-TMT, also known as MK-2870) to see if it can help ...
Phase
Interventional
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FRAmework-01: A Two-Part Phase 3 Study of LY4170156 versus Chemotherapy or Mirvetuximab Soravtansine in Platinum-Resistant Ovarian Cancer and LY4170156 plus Bevacizumab versus Platinum-Based Chemotherapy plus Bevacizumab in Platinum-Sensitive Ovarian Cancer
This is a Phase 3 study testing a new medicine called LY4170156 (an investigational antibody-drug conjugate) targeting FRa for patients with advanced ovarian cancer whose ...
Phase
Interventional
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Randomized Clinical Trial of Postpartum Hypertension Management
The purpose of this study is to determine whether intensive postpartum blood pressure monitoring program leads to better cardiovascular outcomes and prevents future hypertension. This ...Phase N/A Interventional
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Comparing Health Interventions for Maternal Equity
The purpose of this research is to promote healthy maternal weight throughout pregnancy and infancy and to inform the effectiveness of the study interventions on ...Phase N/A Interventional
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A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab vs Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer
This study is being done to see if the overall survival or improvement of the recurrence-free survival from cervical cancer can be increased by adding ...Phase
Interventional
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A Phase 3 Randomized Open-label Study of Rinatabart Sesutecan (Rina-S) versus Treatment of Investigator s Choice (IC) in Patients with Endometrial Cancer After Platinum-Based Chemotherapy and PD(L)-1 Therapy
This is a Phase 3 randomized, open-label study testing the investigational drug Rinatabart Sesutecan (Rina-S) in people with endometrial cancer. Rinatabart Sesutecan (Rina-S), also known ...
Phase
Interventional
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Accelerated Partial breast radiotherapy Study of a personalized Holder for prone breast Immobilization to Enhance Local Delivery (SHIELD)
This is a non-randomized study that looks at how well, how safely, and how easily a medical device called VENUS SHELL™ can be used during ...
Phase N/A Interventional
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RADIation after no Axillary Nodal Sampling (RADIANS)
This is a single arm, pilot, prospective study to evaluate the safety of partial breast irradiation in women who undergo breast conserving surgery without SLNB ...Phase
Interventional
