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GOG-3082 - Phase 1b/2 Basket Study of ACR-368 as Monotherapy and in Combination with Gemcitabine in Adult Subjects with Platinum-Resistant Ovarian Carcinoma Endometrial Adenocarcinoma and Urothelial Carcinoma Based on Acrivon OncoSignature Status
This is a clinical study to test a drug called ACR-368 (also known as Prexasertib) for the treatment of ovarian, endometrial, and urothelial cancer that ...
Phase
Interventional
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A First-in-Human Phase 1a/1b Trial to Assess the Safety Tolerability and Preliminary Efficacy of LY4170156 an Antibody-Drug Conjugate Targeting Folate Receptor a Expressing Tumor Cells in Participants with Selected Advanced Solid Tumors
This study will test a new drug called LY4170156, an antibody drug conjugate (ADC) to see how it works in the body, and if it ...
Phase
Interventional
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NEST Study: Neuro-Environmental Study of Fetal Developmental Trajectories
Our goal is to learn how mothers and babies are connected at important developmental stages, during pregnancy and beyond. We hope to understand more about ...Phase N/A
Non-Interventional
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Digi-Moms: A Wearables and AI Framework for Early Detection of Cardiometabolic Complications in Pregnancy
The purpose of this research study is to see how well digital health devices can monitor the health of patients during pregnancy. Patients will be ...Phase N/A Non-Interventional
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Fetal Ebstein Anomaly or Tricuspid Valve Dysplasia (FEAT) Registry
The purpose of this research study is to create a registry of children with a rare heart disease called Ebstein’s anomaly or tricuspid valve ...Phase N/A Non-Interventional
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Biomarker Liquid Observation Of Mothers (BLOOM)
The purpose of this study is to learn more about postpartum depression, a mental health problem that affects some women after they give birth. Mothers ...Phase N/A Non-Interventional
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CBD (Cannabis) Use Surrounding Pregnancy
The purpose of this research study is to investigate the relationship between pregnant women and CBD (cannabidiol) use.Phase N/A Non-Interventional
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NRG-BR009: A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy in Premenopausal Patients with pN0-1 ER Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score = 25 (OFSET)
This study wants to see if giving extra chemotherapy (adjuvant chemotherapy (ACT) to ovarian function suppression plus endocrine therapy) helps premenopausal women with early-stage breast ...
Phase
Interventional
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A Multicenter Randomized Double-Blind Parallel-Group Dose-Controlled Study Evaluating the Safety and Efficacy of RE104 for Injection in the Treatment of Patients with Postpartum Depression (PPD)
The purpose of collecting your pregnancy information is to see if RE104 has any effects on pregnancy, its outcome, and the birth and health of ...Phase
Interventional
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PATH Inventprise Inc. Phase 1/2 Group B Streptococcus Investigational Vaccine Clinical Trial
The purpose of this study is to gain understanding of the safety, tolerability, and immunogenicity of a new Group B streptococcus (GBS) investigational vaccine (IVT ...Phase
Interventional
