-
A First-in-Human Phase 1a/1b Trial to Assess the Safety Tolerability and Preliminary Efficacy of LY4170156 an Antibody-Drug Conjugate Targeting Folate Receptor a Expressing Tumor Cells in Participants with Selected Advanced Solid Tumors
This study will test a new drug called LY4170156, an antibody drug conjugate (ADC) to see how it works in the body, and if it ...
Phase
Interventional
-
NEST Study: Neuro-Environmental Study of Fetal Developmental Trajectories
Our goal is to learn how mothers and babies are connected at important developmental stages, during pregnancy and beyond. We hope to understand more about ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
-
Digi-Moms: A Wearables and AI Framework for Early Detection of Cardiometabolic Complications in Pregnancy
The purpose of this research study is to see how well digital health devices can monitor the health of patients during pregnancy. Patients will be ...Phase N/A Non-Interventional
-
Biomarker Liquid Observation Of Mothers (BLOOM)
The purpose of this study is to learn more about postpartum depression, a mental health problem that affects some women after they give birth. Mothers ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
-
NRG-BR009: A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy in Premenopausal Patients with pN0-1 ER Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score = 25 (OFSET)
This study wants to see if giving extra chemotherapy (adjuvant chemotherapy (ACT) to ovarian function suppression plus endocrine therapy) helps premenopausal women with early-stage breast ...
Phase
Interventional
-
The Anti-Inflammatory Effects of Milk-Derived Extracellular Vesicles in Preterm Infant
The purpose of this study is to examine and compare Milk-Derived Extracellular Vesicles (EVs) in three types of milk: mothers' own milk, donor milk, and ...Phase N/A Non-Interventional
-
Randomized Evaluation of Bromocriptine in Myocardial Recovery Therapy (REBIRTH) for Peripartum Cardiomyopathy
The purpose of the study is to test the use of a drug called bromocriptine for women who have a condition called “Peripartum cardiomyopathy” or ...Phase
Interventional
-
EXpanding Prenatal cell free DNA screening Across moNogenic Disorders (EXPAND)
The purpose of this research is to develop and validate a single gene Non-Invasive Prenatal Test. The development of this investigational single-gene noninvasive prenatal testing ...Phase N/A Non-Interventional
-
Defining the Impact of Peyronie s Disease on Sexual Quality of Life for Partners
In this study we will interview female partners of patients with Peyronie's disease about the impact of the disease on their sexual quality of ...Phase N/A Non-Interventional
-
Phase 3 Randomized Open-label Multicenter Study to Compare the Efficacy and Safety of Sacituzumab Tirumotecan in Combination with Pembrolizumab Versus Pembrolizumab Alone as First-line Maintenance Treatment in Participants with Mismatch Repair Proficient Endometrial Cancer (TroFuse-033/GOG-3119/ENGOT-en29)
This is a Phase 3 trial testing whether the study medicine sacituzumab tirumotecan (an antibody-drug conjugate, also known as sac-TMT, or MK-2870), when given in ...
Phase
Interventional
