Displaying 30 (all) recruiting clinical trials.
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TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE BREAST CANCER
The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving ...Phase
Interventional
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Heart Attack Research Program (HARP)
The Heart Attack Research Program (HARP) is a multi-discipline and mutli-center study that incorporates clinical and basic science and population health to investigate mechanisms of ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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CivaTech Oncology:Feasibility study to treat lung cancer with the permanently implantable LDR CivaSheet
This is a feasibility study to determine the usefulness of a brachytherapy device that utilizes active components (palladium-103) of standard devices in a novel configuration ...Phase
Interventional
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Biomarkers for preterm births using non-invasive samples
Preterm delivery is a leading cause of neonatal mortality and continues to be a major public health concern. Although some pregnant women will present with ...Phase N/A Non-Interventional
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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly
Fetal complete (i.e., third degree) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally ...Phase
Interventional
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Reach Out Stay Strong Essentials for mothers of newborns (ROSE) Adaptation for Chinese American mothers
We are conducting a cultural adaptation and pilot study of a postpartum depression prevention intervention among pregnant Chinese American women. Once we establish feasibility and ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase 1 First in human Dose Escalation and Expansion Multicenter Study of XMT-1660 in Participants with Solid Tumors
The proposed first-in-human study of XMT-1660 will be a Phase 1, open-label trial of XMT-1660 in previously treated participants with metastatic TNBC, HR+/HER2- or ...Phase
Interventional
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A Phase 1/2a Multicenter Open-Label First in Human Study to Assess the Safety Tolerability Pharmacokinetics and Preliminary Antitumor Activity of DB-1303 in Patients with Advanced/Metastatic Solid Tumors
This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303 in subjects with advanced solid tumors that ...Phase
Interventional
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A Phase 3 Randomized Placebo-Controlled Double-Blind Multicenter Trial of Selinexor in Maintenance Therapy After Systemic Therapy for Patients with P53 Wild-Type Advanced or Recurrent Endometrial Carcinoma (GOG 3083)
The purpose of this research study is to further evaluate the safety and effectiveness of selinexor for maintenance in patients with TP53 wild-type endometrial cancer.Phase
Interventional
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A Phase 1b/2 Open-label Umbrella Study to Evaluate Safety and Efficacy of Elacestrant in Various Combinations in Patients with Metastatic Breast Cancer (ELEVATE)
This is a multicenter, Phase 1b/2 trial. The Phase 1b part of the trial aims to determine the RP2D of elacestrant when administered in ...Phase
Interventional
