Displaying 713 (all) recruiting clinical trials.
-
A Phase 1/2 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 in Patients with Advanced NSCLC and Other Solid Tumors (ALKOVE-1)
A Phase 1/2 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 in Patients with Advanced NSCLC and Other Solid Tumors (ALKOVE-1)Phase
Interventional
-
A Phase IB Study to Determine the Safety and Tolerability of Canakinumab and Tislelizumab in Combination with Nab-Paclitaxel and Gemcitabine in the Neo-adjuvant Treatment of Patients with Pancreatic Cancer
Single Arm Phase Ib study at fixed dose of standard of care chemotherapy and anti PD1 and IL1b to evaluate the safety and preliminary toxicity ...Phase
Interventional
-
Promoting wellness in individuals with traumatic brain injury: A randomized trial assessing the effectiveness of the mindfulness exercise nutrition to optimize resilience (MENTOR) program
This randomized trial aims to determine the effectiveness of an online wellness intervention program focused on mindfulness, physical activity, and nutrition in individuals with traumatic ...Phase N/A Interventional
-
AFFIRM: A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
This is a Phase 4 multicenter evaluation of seladelpar, administered as a once-daily oral capsule, in a randomized, double-blind, placebo-controlled, parallel-group study in patients with ...Phase
Interventional
-
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE VIABAHN VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients with Complex Iliac Occlusive Disease
To demonstrate the superiority of the VBX Device for primary patency when compared to bare metal stenting in complex iliac occlusive disease.Phase N/A Interventional
-
Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)
The prevalence of Alzheimer disease (AD) is high and projected to increase. Further, epidemiological data suggests that ~15% of AD risk may be attributed to ...Phase
Interventional
-
A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis
The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic product (LBP)containing a fixed ...Phase
Interventional
-
Developing a Novel Neural marker for Assessing Pathological Social Interactions
We hypothesize that pathological social interactions like those observed in Autism, arise from a failure by patients to appropriately model the thoughts and plans of ...Phase N/A
Non-Interventional
-
Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients A Pragmatic Trial (EVOLUTION).
This research study is being conducted to determine whether switching to an IL23 inhibitor (guselkumab) is more effective than switching to a second TNFi (golimumab ...Phase N/A Interventional
-
Assessing dysarthria severity before and after neurosurgical procedures: A prospective longitudinal study in patients with refractory movement disorders
Subjects undergoing the neurosurgical high intensity focused ultrasound (HIFU) procedure as part of their standard of care for Essential Tremor (ET) will perform three sessions ...Phase N/A Non-Interventional
