Displaying 545 (all) recruiting clinical trials.
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SUNRAY-01 A Global Pivotal Study in Participants with KRAS G12C-Mutant Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing FirstLine Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in those with PD-L1 expression =50% or LY3537982 and Pembrolizumab Pemetrexed Platinum vs Placebo and Pembrolizumab Pemetrexed Platinum regardless of PD-L1 Expression
This study is testing two different treatments (LY3537982 in combination with pembrolizumab against a placebo combined with pembrolizumab) for a cancer called KRAS G12C-mutant NSCLC ...
Phase
Interventional
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A Phase 3 Randomized Double-blind Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants with Resected Stage II IIIA IIIB (N2) Non-small Cell Lung Cancer
This clinical study will evaluate V940 plus pembrolizumab versus placebo plus pembrolizumab for the adjuvant treatment of completely resected (R0) Stage II to IIIB (N2 ...Phase
Interventional
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A Phase 1 Multicenter Open-Label Study of CB-010 a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
T cells are an integral part of the immune system that kills cancer cells in the body. T cells have been harvested from peripheral blood ...Phase
Interventional
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NYULH Abetalipoproteinemia & Related Disorders Biorepository
This protocol is to establish a patient registry and biospecimen repository for ultra-rare disease abetalipoproteinemia, hypobetalipoproteinemia and chylomicron retention disease patients.Phase N/A
Non-Interventional
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MAGNITUDE: A Phase 3 Multinational Multicenter Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants with Transthyretin Amyloidosis with Cardiomyopathy (ATTR-CM)
This trial is recruiting patients with a condition known as Transthyretin (TTR) Amyloidosis with Cardiomyopathy or ATTR-CM. In individuals with this condition, the heart muscle ...Phase
Interventional
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The (IRAD) International Registry for Acute Aortic Dissection
The purpose of this study is to collect information regarding your medical condition for a registry. The aim of the registry is to document a ...Phase N/A Non-Interventional
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A SINGLE-CENTER OBSERVATIONAL STUDY OF PAIN PHENOTYPES IN PSORIATIC ARTHRITIS
This study is an observational study of individuals with psoriatic arthritis (PsA) to define types of pain. We aim to better understand the prevalence of ...Phase N/A Non-Interventional
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Time to Union: A Comparison of the Medartis Scaphoid Volar Locking Plate and Headless Compression Screws for Treatment of Scaphoid Nonunion
The purpose of this study is to determine the optimal approach for treating scaphoid nonunions surgically. A scaphoid nonunion occurs when you have a fractured ...Phase N/A Non-Interventional
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Microbial and Host Biomarkers for Endotyping Venous Thromboembolism Patients
This research aims to understand the differences between blood clotting caused by viruses affecting the whole body versus those affecting the lungs, and how different ...Phase N/A Non-Interventional
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A SINGLE-CENTER OBSERVATIONAL STUDY OF CLINICAL OUTCOMES FOLLOWING TREATMENT OF LEIOMYOMA WITH COMBINATION THERAPY UTILIZING GNRH ANALOGS AND TRANSCERVICAL FIBROID ABLATION
This is a prospective cohort study of patients who will receive TFA following medical therapy for fibroid care between 1/2023 and 1/2024 at ...Phase N/A Non-Interventional
