Displaying 550 (all) recruiting clinical trials.
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A Phase III Randomized Double-Blind Placebo-Controlled Non-Inferiority Multi-Center Study of the Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
This study aims to develop evidence-based protocols for managing older patients with systemic lupus erythematosus (SLE), a topic that has been largely overlooked. Hydroxychloroquine (HCQ ...Phase
Interventional
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A Phase 2 double-blind placebo-controlled parallel-group study to assess the safety tolerability pharmacokinetics pharmacodynamics and potential efficacy of multiple doses of ONO-2808 in patients with Multiple System Atrophy (MSA)
The purpose of this clinical research study is to look at the safety and tolerability of the investigational study drug, ONO-2808, and whether it works ...Phase
Interventional
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An Open-Label Multi-Center Retrospective and Prospective Evaluation of Shoulder Arthroplasty Clinical and Radiographic Outcomes
This is an open label, multi-center, retrospective and prospective clinical study. Patients who are to undergo shoulder arthroplasty may be screened for participation. Likewise, patients ...Phase N/A
Non-Interventional
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Tuberous Sclerosis Complex Biosample Repository and Natural History Database Project
The purpose of the project is to learn more about tuberous sclerosis complex (TSC) which may lead to new treatments for conditions that affect different ...Phase N/A Non-Interventional
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Assessment of the Safety and Efficacy of a Combined Cardiac Contractility Modulation and Implantable Cardioverter Defibrillator Device for Subjects with Heart Failure and Reduced Ejection Fraction
The purpose of this study is to determine if the combination of Cardiac Contractility Modulation (CCM®) and implantable cardioverter-defibrillator (ICD), as an investigational device (OPTIMIZER ...Phase N/A Interventional
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A single-center observational study of lifestyle behaviors (diet physical activity and sleep) in adults with psoriatic disease
Psoriasis is a chronic inflammatory skin disease associated with significant public health burden. Interestingly, obesity is a risk factor for the development of psoriasis. Additionally ...Phase N/A Non-Interventional
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MACI Patient Registry and Data Repository
The objective of the Matrix-induced autologous chondrocyte implantation (MACI) Registry is to allow the collection of demographic, treatment, and outcome data at sites in the ...Phase N/A Non-Interventional
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Hand allotransplantation
The purpose of this study is to evaluate functional and aesthetic outcomes of hand composite tissue allografts on patients who have not achieved functional aesthetic ...Phase N/A Interventional
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A Global Prospective Observational Registry of Patients with Pompe Disease
The purpose of this registry is to evaluate clinical outcomes in participants with Pompe disease. This includes what happens to participants who are not on ...Phase N/A Non-Interventional
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Evoked Compound Action Potentials for Parkinson's Disease (eCAP-PD) Study
The purpose of this research is to see whether the study device, the Evoke® SCS System, is safe and works to treat Parkinson’s disease ...Phase N/A Interventional
