Displaying 722 (all) recruiting clinical trials.
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A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute LeukemiaPhase
Interventional
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Organized sports participation among patients who have undergone Ponseti treatment for Idiopathic Clubfoot
A retrospective chart review of patients treated for clubfoot. Participation involves completing a one-time survey asking for demographic, physical activity, and sports participation information. Surveys ...Phase N/A
Non-Interventional
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A Multi-Center Observational Study Assessing the Utility of an Immune Cell Function Assay in a Cardiac Sarcoid Population
Sarcoid is an autoimmune disease that can be found in any and every organ system. The greatest degree of morbidity and mortality comes from cardiac ...Phase N/A Non-Interventional
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Paradoxical Lucidity in Severe End-Stage Dementia: A Mixed Methods Prospective Study
Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal ...Phase N/A Non-Interventional
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A Randomized Comparative Effectiveness Study of Staged Complete Revascularization with Percutaneous Coronary Intervention to Treat Coronary Artery Disease vs Medical Management Alone in Patients with Symptomatic Aortic Valve Stenosis undergoing Elective Transfemoral Transcatheter Aortic Valve Replacement: The COMPLETE TAVR Study
This study is being conducted in Aortic Stenosis patients who have undergone successful TAVR with a balloon expandable heart valve who also have coronary artery ...Phase N/A Interventional
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Depression treatment and A dynamics: A study of Alzheimer s disease risk (ABD Study)
The study will use a randomized 8-week double-blind placebo controlled parallel trial using escitalopram to test the associations between depressive symptoms (captured by the MADRS ...Phase
Interventional
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Site for Understanding health disparities in Pakistani Bangladeshi and Asian Indian immigrants: the role of socio-cultural context acculturation and resilience resources - Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study Expansion New York Site
Site for This protocol describes a mixed methods study that leverages the infrastructure of an ongoing MASALA study in Chicago and San Francisco to enroll ...Phase N/A Non-Interventional
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The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis (SAVVE) Study Trial
To assess the safety and effectiveness of the Hancock Jaffe VenoValve for the treatment of patients with deep venous valvular insufficiency A prospective, non-blinded, single-arm ...Phase
Interventional
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Reach Out Stay Strong Essentials for mothers of newborns (ROSE) Adaptation for Chinese American mothers
We are conducting a cultural adaptation and pilot study of a postpartum depression prevention intervention among pregnant Chinese American women. Once we establish feasibility and ...Phase
Interventional
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A randomized phase II trial of adjuvant trastuzumab emtansine (T-DM1) followed by subcutaneous trastuzumab versus paclitaxel in combination with subcutaneous trastuzumab for Stage I HER2-positive breast cancer (ATEMPT 2.0)
This is a randomized phase II adjuvant study for women and men with Stage I HER2-positive invasive breast cancer. At least 500 eligible patients will ...Phase
Interventional
