Displaying 478 (all) recruiting clinical trials.
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Targeting Hyaluronan Accumulation Through Exercise in T2DM
The purpose of this study is to examine the effects of exercise on hyaluronan (HA) accumulation in calf muscles. HA is seen in skeletal muscle ... -
Intra-Individual Variability in Cognitive Performance as a Marker of Prodromal Disability in MS
The purpose of this research study is to develop a way of detecting the very early signs of cognitive decline in patients with Multiple Sclerosis ... -
A Multicenter Randomized Double-Blind Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn s Disease
The purpose of this study is to assess an investigational drug called etrasimod (also referred to as the “study drug”) in the treatment of Crohn ... -
A Phase II Study of Biomarker Driven Early Discontinuation of Anti-PD-1 Therapy in Patients with Advanced Melanoma (PET-Stop) [EA6192]
The purpose of the study is to evaluate and determine how well biomarkers on PET/CT imaging drive early discontinuation of anti-PD-1 therapy in patients ... -
A Pilot Randomized Controlled Trial of Integrated Supportive and Nephrology Care versus Usual Care
The purpose of this study is to test the impact of adding a form of care known as palliative, or supportive, care to your usual ... -
A novel Phase 2 double-blind randomized controlled clinical trial to evaluate the efficacy of centrally acting non-toxic ACE inhibition in cognitive impairment associated with SLE
This research study is being done to test the effects of centrally-acting ACE inhibitor, named lisinopril, on resting metabolism in the brain and on cognitive ... -
Interventional randomized double-blind parallel-group placebo-controlled multi-centre study to assess the efficacy safety and tolerability of Lu AF82422 in patients with Multiple System Atrophy
The purpose of this study is to find out whether a potential new treatment, the investigational drug Lu AF82422, is safe and effective in people ... -
AHCRN Registry: Characterizing Patient Populations in the Adult Hydrocephalus Clinical Research Network (AHCRN)
The purpose of this research project is to develop a patient registry, or database, for data collected during routine medical care of patients with hydrocephalus ... -
Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease
The purpose of this study is to learn more about whether nebulized hypertonic saline can help improve symptoms and clearance of mycobacteria. Hypertonic saline (7 ... -
A Phase 2 Study of BA3011 Alone and in Combination with Nivolumab in Adult Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) Who Had Prior Disease Progression on a PD-1/L-1 Inhibitor
The purpose of the study is designed to evaluate the efficacy and safety of BA3011 alone and in combination with nivolumab in patients with AXL-expressing ...